Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer

Antonio González-Martín, Bhavana Pothuri, Ignace Vergote, René DePont Christensen, Whitney Graybill, Mansoor R Mirza, Colleen McCormick, Domenica Lorusso, Paul Hoskins, Gilles Freyer, Klaus Baumann, Kris Jardon, Andrés Redondo, Richard G Moore, Christof Vulsteke, Roisin E O'Cearbhaill, Bente Lund, Floor Backes, Pilar Barretina-Ginesta, Ashley F HaggertyMaria J Rubio-Pérez, Mark S Shahin, Giorgia Mangili, William H Bradley, Ilan Bruchim, Kaiming Sun, Izabela A Malinowska, Yong Li, Divya Gupta, Bradley J Monk, PRIMA/ENGOT-OV26/GOG-3012 Investigators

Research output: Contribution to journalJournal articleResearchpeer-review

151 Citations (Scopus)
Original languageEnglish
JournalThe New England Journal of Medicine
Volume381
Issue number25
Pages (from-to)2391-2402
Number of pages12
ISSN0028-4793
DOIs
Publication statusPublished - 19 Dec 2019

Keywords

  • Administration, Oral
  • Adult
  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents/therapeutic use
  • Combined Modality Therapy
  • Double-Blind Method
  • Female
  • Humans
  • Indazoles/adverse effects
  • Maintenance Chemotherapy
  • Middle Aged
  • Nausea/chemically induced
  • Ovarian Neoplasms/drug therapy
  • Piperidines/adverse effects
  • Poly(ADP-ribose) Polymerase Inhibitors/adverse effects
  • Progression-Free Survival
  • Quality of Life
  • Survival Analysis

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    González-Martín, A., Pothuri, B., Vergote, I., DePont Christensen, R., Graybill, W., Mirza, M. R., McCormick, C., Lorusso, D., Hoskins, P., Freyer, G., Baumann, K., Jardon, K., Redondo, A., Moore, R. G., Vulsteke, C., O'Cearbhaill, R. E., Lund, B., Backes, F., Barretina-Ginesta, P., ... PRIMA/ENGOT-OV26/GOG-3012 Investigators (2019). Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer. The New England Journal of Medicine, 381(25), 2391-2402. https://doi.org/10.1056/NEJMoa1910962