Outcomes among non-Western immigrant patients and Danish-born patients with acute myeloid Leukaemia: A Danish population-based cohort study

Daniel Tuyet Kristensen; Mikkel Runason Simonsen; Anne Stidsholt Roug; Claus Werenberg Marcher; Andreas Due Ørskov; Anne Louise Tøllbøll Sørensen; Tarec Christoffer El-Galaly; Joachim Baech

doi:10.1111/bjh.19850

Outcomes among non-Western immigrant patients and Danish-born patients with acute myeloid Leukaemia: A Danish population-based cohort study

Daniel Tuyet Kristensen^*, Mikkel Runason Simonsen, Anne Stidsholt Roug, Claus Werenberg Marcher, Andreas Due Ørskov, Anne Louise Tøllbøll Sørensen, Tarec Christoffer El-Galaly, Joachim Baech

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Abstract

Non-Western immigrant patients (NWIPs) may be a vulnerable population when diagnosed and treated for acute myeloid leukaemia (AML). Here we report selected quality parameters related to diagnosis, treatment, and outcome of newly diagnosed AML among NWIPs (n = 119) and Danish-born patients (DBPs) (n = 4689). No adjusted differences were observed for time-to-diagnosis, time-to-treatment, treatment allocation, rates of complete remission, early death, allogeneic stem cell transplantation, and overall survival between NWIPs and DBPs. Among patients allocated for intensive chemotherapy, NWIPs were less likely to participate in clinical trials. The findings highlight equitable AML care but underscore the need to enhance NWIP participation in clinical trials.

Original language	English
Journal	British Journal of Haematology
Number of pages	6
ISSN	0007-1048
DOIs	https://doi.org/10.1111/bjh.19850
Publication status	E-pub ahead of print - 22 Oct 2024

Bibliographical note

Keywords

acute myeloid leukaemia
clinical outcome
clinical trial participation
immigrant patients
non-western immigrants

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Kristensen, D. T., Simonsen, M. R., Roug, A. S., Marcher, C. W., Ørskov, A. D., Sørensen, A. L. T., El-Galaly, T. C., & Baech, J. (2024). Outcomes among non-Western immigrant patients and Danish-born patients with acute myeloid Leukaemia: A Danish population-based cohort study. British Journal of Haematology. Advance online publication. https://doi.org/10.1111/bjh.19850

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title = "Outcomes among non-Western immigrant patients and Danish-born patients with acute myeloid Leukaemia: A Danish population-based cohort study",

abstract = "Non-Western immigrant patients (NWIPs) may be a vulnerable population when diagnosed and treated for acute myeloid leukaemia (AML). Here we report selected quality parameters related to diagnosis, treatment, and outcome of newly diagnosed AML among NWIPs (n = 119) and Danish-born patients (DBPs) (n = 4689). No adjusted differences were observed for time-to-diagnosis, time-to-treatment, treatment allocation, rates of complete remission, early death, allogeneic stem cell transplantation, and overall survival between NWIPs and DBPs. Among patients allocated for intensive chemotherapy, NWIPs were less likely to participate in clinical trials. The findings highlight equitable AML care but underscore the need to enhance NWIP participation in clinical trials.",

keywords = "acute myeloid leukaemia, clinical outcome, clinical trial participation, immigrant patients, non-western immigrants",

author = "Kristensen, {Daniel Tuyet} and Simonsen, {Mikkel Runason} and Roug, {Anne Stidsholt} and Marcher, {Claus Werenberg} and {\O}rskov, {Andreas Due} and S{\o}rensen, {Anne Louise T{\o}llb{\o}ll} and El-Galaly, {Tarec Christoffer} and Joachim Baech",

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month = oct,

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doi = "10.1111/bjh.19850",

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journal = "British Journal of Haematology",

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T1 - Outcomes among non-Western immigrant patients and Danish-born patients with acute myeloid Leukaemia: A Danish population-based cohort study

AU - Kristensen, Daniel Tuyet

AU - Simonsen, Mikkel Runason

AU - Roug, Anne Stidsholt

AU - Marcher, Claus Werenberg

AU - Ørskov, Andreas Due

AU - Sørensen, Anne Louise Tøllbøll

AU - El-Galaly, Tarec Christoffer

AU - Baech, Joachim

PY - 2024/10/22

Y1 - 2024/10/22

N2 - Non-Western immigrant patients (NWIPs) may be a vulnerable population when diagnosed and treated for acute myeloid leukaemia (AML). Here we report selected quality parameters related to diagnosis, treatment, and outcome of newly diagnosed AML among NWIPs (n = 119) and Danish-born patients (DBPs) (n = 4689). No adjusted differences were observed for time-to-diagnosis, time-to-treatment, treatment allocation, rates of complete remission, early death, allogeneic stem cell transplantation, and overall survival between NWIPs and DBPs. Among patients allocated for intensive chemotherapy, NWIPs were less likely to participate in clinical trials. The findings highlight equitable AML care but underscore the need to enhance NWIP participation in clinical trials.

AB - Non-Western immigrant patients (NWIPs) may be a vulnerable population when diagnosed and treated for acute myeloid leukaemia (AML). Here we report selected quality parameters related to diagnosis, treatment, and outcome of newly diagnosed AML among NWIPs (n = 119) and Danish-born patients (DBPs) (n = 4689). No adjusted differences were observed for time-to-diagnosis, time-to-treatment, treatment allocation, rates of complete remission, early death, allogeneic stem cell transplantation, and overall survival between NWIPs and DBPs. Among patients allocated for intensive chemotherapy, NWIPs were less likely to participate in clinical trials. The findings highlight equitable AML care but underscore the need to enhance NWIP participation in clinical trials.

KW - acute myeloid leukaemia

KW - clinical outcome

KW - clinical trial participation

KW - immigrant patients

KW - non-western immigrants

UR - http://www.scopus.com/inward/record.url?scp=85207315706&partnerID=8YFLogxK

U2 - 10.1111/bjh.19850

DO - 10.1111/bjh.19850

M3 - Journal article

C2 - 39439197

SN - 0007-1048

JO - British Journal of Haematology

JF - British Journal of Haematology

ER -

Outcomes among non-Western immigrant patients and Danish-born patients with acute myeloid Leukaemia: A Danish population-based cohort study

Abstract

Bibliographical note

Keywords

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