Abstract
In most cases, tissue injuries lead to inflammation and sensitization. From a neuroscience perspective, this is why one usually hurts when one is injured. Peripheral sensitization is an essential principle in pain science, and it is associated with hyperalgesia, inflammation, and clinical pain conditions, including acute injuries and rheumatological diseases. This editorial explains peripheral sensitization, neurogenic inflammation, and the axon reflex, as well as the role of second messengers and peptidergic C-fibers.
| Original language | English |
|---|---|
| Journal | Journal of Orthopaedic and Sports Physical Therapy |
| Volume | 52 |
| Issue number | 6 |
| Pages (from-to) | 303-306 |
| Number of pages | 4 |
| ISSN | 0190-6011 |
| DOIs | |
| Publication status | Published - Jun 2022 |
Keywords
- musculoskeletal pain
- neuroscience
- pain
- pain education