Papillary microcarcinoma of the thyroid gland: is the immunohistochemical expression of cyclin D1 or galectin-3 in primary tumour an indicator of metastatic disease?

Stefano Christian Londero; Christian Godballe; Annelise Krogdahl; Lars Bastholt; Lena Specht; Christian Hjort Sørensen; Henrik Baymler Pedersen; Ulrik Pedersen; Peer Christiansen

doi:10.1080/02841860701630242

Papillary microcarcinoma of the thyroid gland: is the immunohistochemical expression of cyclin D1 or galectin-3 in primary tumour an indicator of metastatic disease?

Stefano Christian Londero, Christian Godballe, Annelise Krogdahl, Lars Bastholt, Lena Specht, Christian Hjort Sørensen, Henrik Baymler Pedersen, Ulrik Pedersen, Peer Christiansen

Research output: Contribution to journal › Journal article › Research › peer-review

15 Citations (Scopus)

Abstract

Papillary microcarcinomas (PMC) of the thyroid gland are defined according to The WHO Committee as papillary carcinomas measuring 10 mm or less in diameter. A large proportion of these tumours are found coincidentally in the treatment of symptomatic goitre and most cases follow an indolent course with an excellent prognosis. However, a more aggressive behaviour with regional and distant metastases does occur. The aim of this study was to evaluate if the immunohistochemical markers cyclin D1 or galectin-3 might indicate the presence of metastatic disease in patients with PMC at the time of diagnosis.

Original language	English
Journal	Acta Oncologica
Volume	47
Pages (from-to)	451-7
Number of pages	7
ISSN	0284-186X
DOIs	https://doi.org/10.1080/02841860701630242
Publication status	Published - 2008
Externally published	Yes

Keywords

Adult
Carcinoma, Papillary
Cyclin D
Cyclins
Databases, Factual
Denmark
Female
Galectin 3
Gene Expression Regulation, Neoplastic
Humans
Male
Middle Aged
Neoplasm Proteins
Thyroid Neoplasms
Tumor Markers, Biological

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10.1080/02841860701630242

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Londero, S. C., Godballe, C., Krogdahl, A., Bastholt, L., Specht, L., Sørensen, C. H., Pedersen, H. B., Pedersen, U., & Christiansen, P. (2008). Papillary microcarcinoma of the thyroid gland: is the immunohistochemical expression of cyclin D1 or galectin-3 in primary tumour an indicator of metastatic disease? Acta Oncologica, 47, 451-7. https://doi.org/10.1080/02841860701630242

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title = "Papillary microcarcinoma of the thyroid gland: is the immunohistochemical expression of cyclin D1 or galectin-3 in primary tumour an indicator of metastatic disease?",

abstract = "Papillary microcarcinomas (PMC) of the thyroid gland are defined according to The WHO Committee as papillary carcinomas measuring 10 mm or less in diameter. A large proportion of these tumours are found coincidentally in the treatment of symptomatic goitre and most cases follow an indolent course with an excellent prognosis. However, a more aggressive behaviour with regional and distant metastases does occur. The aim of this study was to evaluate if the immunohistochemical markers cyclin D1 or galectin-3 might indicate the presence of metastatic disease in patients with PMC at the time of diagnosis.",

keywords = "Adult, Carcinoma, Papillary, Cyclin D, Cyclins, Databases, Factual, Denmark, Female, Galectin 3, Gene Expression Regulation, Neoplastic, Humans, Male, Middle Aged, Neoplasm Proteins, Thyroid Neoplasms, Tumor Markers, Biological",

author = "Londero, {Stefano Christian} and Christian Godballe and Annelise Krogdahl and Lars Bastholt and Lena Specht and S{\o}rensen, {Christian Hjort} and Pedersen, {Henrik Baymler} and Ulrik Pedersen and Peer Christiansen",

year = "2008",

doi = "10.1080/02841860701630242",

language = "English",

volume = "47",

pages = "451--7",

journal = "Acta Oncologica",

issn = "0284-186X",

publisher = "Taylor & Francis",

}

Londero, SC, Godballe, C, Krogdahl, A, Bastholt, L, Specht, L, Sørensen, CH, Pedersen, HB, Pedersen, U & Christiansen, P 2008, 'Papillary microcarcinoma of the thyroid gland: is the immunohistochemical expression of cyclin D1 or galectin-3 in primary tumour an indicator of metastatic disease?', Acta Oncologica, vol. 47, pp. 451-7. https://doi.org/10.1080/02841860701630242

Papillary microcarcinoma of the thyroid gland: is the immunohistochemical expression of cyclin D1 or galectin-3 in primary tumour an indicator of metastatic disease? / Londero, Stefano Christian; Godballe, Christian; Krogdahl, Annelise et al.
In: Acta Oncologica, Vol. 47, 2008, p. 451-7.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - Papillary microcarcinoma of the thyroid gland

T2 - is the immunohistochemical expression of cyclin D1 or galectin-3 in primary tumour an indicator of metastatic disease?

AU - Londero, Stefano Christian

AU - Godballe, Christian

AU - Krogdahl, Annelise

AU - Bastholt, Lars

AU - Specht, Lena

AU - Sørensen, Christian Hjort

AU - Pedersen, Henrik Baymler

AU - Pedersen, Ulrik

AU - Christiansen, Peer

PY - 2008

Y1 - 2008

N2 - Papillary microcarcinomas (PMC) of the thyroid gland are defined according to The WHO Committee as papillary carcinomas measuring 10 mm or less in diameter. A large proportion of these tumours are found coincidentally in the treatment of symptomatic goitre and most cases follow an indolent course with an excellent prognosis. However, a more aggressive behaviour with regional and distant metastases does occur. The aim of this study was to evaluate if the immunohistochemical markers cyclin D1 or galectin-3 might indicate the presence of metastatic disease in patients with PMC at the time of diagnosis.

AB - Papillary microcarcinomas (PMC) of the thyroid gland are defined according to The WHO Committee as papillary carcinomas measuring 10 mm or less in diameter. A large proportion of these tumours are found coincidentally in the treatment of symptomatic goitre and most cases follow an indolent course with an excellent prognosis. However, a more aggressive behaviour with regional and distant metastases does occur. The aim of this study was to evaluate if the immunohistochemical markers cyclin D1 or galectin-3 might indicate the presence of metastatic disease in patients with PMC at the time of diagnosis.

KW - Adult

KW - Carcinoma, Papillary

KW - Cyclin D

KW - Cyclins

KW - Databases, Factual

KW - Denmark

KW - Female

KW - Galectin 3

KW - Gene Expression Regulation, Neoplastic

KW - Humans

KW - Male

KW - Middle Aged

KW - Neoplasm Proteins

KW - Thyroid Neoplasms

KW - Tumor Markers, Biological

U2 - 10.1080/02841860701630242

DO - 10.1080/02841860701630242

M3 - Journal article

SN - 0284-186X

VL - 47

SP - 451

EP - 457

JO - Acta Oncologica

JF - Acta Oncologica

ER -

Papillary microcarcinoma of the thyroid gland: is the immunohistochemical expression of cyclin D1 or galectin-3 in primary tumour an indicator of metastatic disease?

Abstract

Keywords

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