Partial oral treatment of endocarditis

Kasper Iversen; Nis Høst; Niels Eske Bruun; Hanne Elming; Bettina Pump; Jens Jørgen Christensen; Sabine Gill; Flemming Rosenvinge; Henrik Wiggers; Kurt Fuursted; Claus Holst-Hansen; Eva Korup; Henrik Carl Schønheyder; Christian Hassager; Dan Høfsten; Jannik Helweg Larsen; Claus Moser; Nikolaj Ihlemann; Henning Bundgaard

doi:10.1016/j.ahj.2012.11.006

Partial oral treatment of endocarditis

Kasper Iversen, Nis Høst, Niels Eske Bruun, Hanne Elming, Bettina Pump, Jens Jørgen Christensen, Sabine Gill, Flemming Rosenvinge, Henrik Wiggers, Kurt Fuursted, Claus Holst-Hansen, Eva Korup, Henrik Carl Schønheyder, Christian Hassager, Dan Høfsten, Jannik Helweg Larsen, Claus Moser, Nikolaj Ihlemann, Henning Bundgaard

Research output: Contribution to journal › Journal article › Research › peer-review

35 Citations (Scopus)

Abstract

Guidelines for the treatment of left-sided infective endocarditis (IE) recommend 4 to 6 weeks of intravenous antibiotics. Conversion from intravenous to oral antibiotics in clinically stabilized patients could reduce the side effects associated with intravenous treatment and shorten the length of hospital stay. Evidence supporting partial oral therapy as an alternative to the routinely recommended continued parenteral therapy is scarce, although observational data suggest that this strategy may be safe and effective.

Original language	English
Journal	American Heart Journal
Volume	165
Issue number	2
Pages (from-to)	116-22
Number of pages	7
ISSN	0002-8703
DOIs	https://doi.org/10.1016/j.ahj.2012.11.006
Publication status	Published - 2013

Keywords

Administration, Oral
Adult
Aged
Anti-Bacterial Agents
Dose-Response Relationship, Drug
Endocarditis, Bacterial
Female
Follow-Up Studies
Humans
Injections, Intravenous
Male
Middle Aged
Prospective Studies
Treatment Outcome

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Iversen, K., Høst, N., Bruun, N. E., Elming, H., Pump, B., Christensen, J. J., Gill, S., Rosenvinge, F., Wiggers, H., Fuursted, K., Holst-Hansen, C., Korup, E., Schønheyder, H. C., Hassager, C., Høfsten, D., Larsen, J. H., Moser, C., Ihlemann, N., & Bundgaard, H. (2013). Partial oral treatment of endocarditis. American Heart Journal, 165(2), 116-22. https://doi.org/10.1016/j.ahj.2012.11.006

@article{895cdac9b84c47a38c5ef08f923e1ae9,

title = "Partial oral treatment of endocarditis",

abstract = "Guidelines for the treatment of left-sided infective endocarditis (IE) recommend 4 to 6 weeks of intravenous antibiotics. Conversion from intravenous to oral antibiotics in clinically stabilized patients could reduce the side effects associated with intravenous treatment and shorten the length of hospital stay. Evidence supporting partial oral therapy as an alternative to the routinely recommended continued parenteral therapy is scarce, although observational data suggest that this strategy may be safe and effective.",

keywords = "Administration, Oral, Adult, Aged, Anti-Bacterial Agents, Dose-Response Relationship, Drug, Endocarditis, Bacterial, Female, Follow-Up Studies, Humans, Injections, Intravenous, Male, Middle Aged, Prospective Studies, Treatment Outcome",

author = "Kasper Iversen and Nis H{\o}st and Bruun, {Niels Eske} and Hanne Elming and Bettina Pump and Christensen, {Jens J{\o}rgen} and Sabine Gill and Flemming Rosenvinge and Henrik Wiggers and Kurt Fuursted and Claus Holst-Hansen and Eva Korup and Sch{\o}nheyder, {Henrik Carl} and Christian Hassager and Dan H{\o}fsten and Larsen, {Jannik Helweg} and Claus Moser and Nikolaj Ihlemann and Henning Bundgaard",

year = "2013",

doi = "10.1016/j.ahj.2012.11.006",

language = "English",

volume = "165",

pages = "116--22",

journal = "American Heart Journal",

issn = "0002-8703",

publisher = "Mosby, Inc.",

number = "2",

}

Iversen, K, Høst, N, Bruun, NE, Elming, H, Pump, B, Christensen, JJ, Gill, S, Rosenvinge, F, Wiggers, H, Fuursted, K, Holst-Hansen, C , Korup, E, Schønheyder, HC, Hassager, C, Høfsten, D, Larsen, JH, Moser, C, Ihlemann, N & Bundgaard, H 2013, 'Partial oral treatment of endocarditis', American Heart Journal, vol. 165, no. 2, pp. 116-22. https://doi.org/10.1016/j.ahj.2012.11.006

TY - JOUR

T1 - Partial oral treatment of endocarditis

AU - Iversen, Kasper

AU - Høst, Nis

AU - Bruun, Niels Eske

AU - Elming, Hanne

AU - Pump, Bettina

AU - Christensen, Jens Jørgen

AU - Gill, Sabine

AU - Rosenvinge, Flemming

AU - Wiggers, Henrik

AU - Fuursted, Kurt

AU - Holst-Hansen, Claus

AU - Korup, Eva

AU - Schønheyder, Henrik Carl

AU - Hassager, Christian

AU - Høfsten, Dan

AU - Larsen, Jannik Helweg

AU - Moser, Claus

AU - Ihlemann, Nikolaj

AU - Bundgaard, Henning

PY - 2013

Y1 - 2013

N2 - Guidelines for the treatment of left-sided infective endocarditis (IE) recommend 4 to 6 weeks of intravenous antibiotics. Conversion from intravenous to oral antibiotics in clinically stabilized patients could reduce the side effects associated with intravenous treatment and shorten the length of hospital stay. Evidence supporting partial oral therapy as an alternative to the routinely recommended continued parenteral therapy is scarce, although observational data suggest that this strategy may be safe and effective.

AB - Guidelines for the treatment of left-sided infective endocarditis (IE) recommend 4 to 6 weeks of intravenous antibiotics. Conversion from intravenous to oral antibiotics in clinically stabilized patients could reduce the side effects associated with intravenous treatment and shorten the length of hospital stay. Evidence supporting partial oral therapy as an alternative to the routinely recommended continued parenteral therapy is scarce, although observational data suggest that this strategy may be safe and effective.

KW - Administration, Oral

KW - Adult

KW - Aged

KW - Anti-Bacterial Agents

KW - Dose-Response Relationship, Drug

KW - Endocarditis, Bacterial

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Injections, Intravenous

KW - Male

KW - Middle Aged

KW - Prospective Studies

KW - Treatment Outcome

U2 - 10.1016/j.ahj.2012.11.006

DO - 10.1016/j.ahj.2012.11.006

M3 - Journal article

C2 - 23351813

SN - 0002-8703

VL - 165

SP - 116

EP - 122

JO - American Heart Journal

JF - American Heart Journal

IS - 2

ER -

Partial oral treatment of endocarditis

Abstract

Keywords

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