Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations

Robert R. Edwards, Robert H. Dworkin, Dennis C. Turk, Martin S. Angst, Raymond Dionne, Roy Freeman, Per Hansson, Simon Haroutounian, Lars Arendt-Nielsen, Nadine Attal, Ralf Baron, Joanna Brell, Shay Bujanover, Laurie B. Burke, Daniel Carr, Amy S. Chappell, Penney Cowan, Mila Etropolski, Roger B. Fillingim, Jennifer S. Gewandter & 18 others Nathaniel P. Katz, Ernest A. Kopecky, John D. Markman, George Nomikos, Linda Porter, Bob A. Rappaport, Andrew S. C. Rice, Joseph M. Scavone, Joachim Scholz, Lee S. Simon, Shannon M. Smith, Jeffrey Tobias, Tina Tockarshewsky, Christine Veasley, Mark Versavel, Ajay D. Wasan, Warren Wen, David Yarnitsky

Research output: Contribution to journalReview articleResearchpeer-review

53 Citations (Scopus)
Original languageEnglish
JournalPain
Volume157
Issue number9
Pages (from-to)1851-1871
ISSN0304-3959
DOIs
Publication statusPublished - 2016

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Chronic Pain
Clinical Trials
Analgesics
Pain
Therapeutics
Phase III Clinical Trials
Precision Medicine
Frustration
Patient Care
Sleep
Psychology

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Edwards, R. R., Dworkin, R. H., Turk, D. C., Angst, M. S., Dionne, R., Freeman, R., ... Yarnitsky, D. (2016). Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations. Pain, 157(9), 1851-1871. https://doi.org/10.1097/j.pain.0000000000000602
Edwards, Robert R. ; Dworkin, Robert H. ; Turk, Dennis C. ; Angst, Martin S. ; Dionne, Raymond ; Freeman, Roy ; Hansson, Per ; Haroutounian, Simon ; Arendt-Nielsen, Lars ; Attal, Nadine ; Baron, Ralf ; Brell, Joanna ; Bujanover, Shay ; Burke, Laurie B. ; Carr, Daniel ; Chappell, Amy S. ; Cowan, Penney ; Etropolski, Mila ; Fillingim, Roger B. ; Gewandter, Jennifer S. ; Katz, Nathaniel P. ; Kopecky, Ernest A. ; Markman, John D. ; Nomikos, George ; Porter, Linda ; Rappaport, Bob A. ; Rice, Andrew S. C. ; Scavone, Joseph M. ; Scholz, Joachim ; Simon, Lee S. ; Smith, Shannon M. ; Tobias, Jeffrey ; Tockarshewsky, Tina ; Veasley, Christine ; Versavel, Mark ; Wasan, Ajay D. ; Wen, Warren ; Yarnitsky, David. / Patient phenotyping in clinical trials of chronic pain treatments : IMMPACT recommendations. In: Pain. 2016 ; Vol. 157, No. 9. pp. 1851-1871.
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title = "Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations",
author = "Edwards, {Robert R.} and Dworkin, {Robert H.} and Turk, {Dennis C.} and Angst, {Martin S.} and Raymond Dionne and Roy Freeman and Per Hansson and Simon Haroutounian and Lars Arendt-Nielsen and Nadine Attal and Ralf Baron and Joanna Brell and Shay Bujanover and Burke, {Laurie B.} and Daniel Carr and Chappell, {Amy S.} and Penney Cowan and Mila Etropolski and Fillingim, {Roger B.} and Gewandter, {Jennifer S.} and Katz, {Nathaniel P.} and Kopecky, {Ernest A.} and Markman, {John D.} and George Nomikos and Linda Porter and Rappaport, {Bob A.} and Rice, {Andrew S. C.} and Scavone, {Joseph M.} and Joachim Scholz and Simon, {Lee S.} and Smith, {Shannon M.} and Jeffrey Tobias and Tina Tockarshewsky and Christine Veasley and Mark Versavel and Wasan, {Ajay D.} and Warren Wen and David Yarnitsky",
year = "2016",
doi = "10.1097/j.pain.0000000000000602",
language = "English",
volume = "157",
pages = "1851--1871",
journal = "Pain",
issn = "0304-3959",
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Edwards, RR, Dworkin, RH, Turk, DC, Angst, MS, Dionne, R, Freeman, R, Hansson, P, Haroutounian, S, Arendt-Nielsen, L, Attal, N, Baron, R, Brell, J, Bujanover, S, Burke, LB, Carr, D, Chappell, AS, Cowan, P, Etropolski, M, Fillingim, RB, Gewandter, JS, Katz, NP, Kopecky, EA, Markman, JD, Nomikos, G, Porter, L, Rappaport, BA, Rice, ASC, Scavone, JM, Scholz, J, Simon, LS, Smith, SM, Tobias, J, Tockarshewsky, T, Veasley, C, Versavel, M, Wasan, AD, Wen, W & Yarnitsky, D 2016, 'Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations' Pain, vol. 157, no. 9, pp. 1851-1871. https://doi.org/10.1097/j.pain.0000000000000602

Patient phenotyping in clinical trials of chronic pain treatments : IMMPACT recommendations. / Edwards, Robert R.; Dworkin, Robert H.; Turk, Dennis C.; Angst, Martin S.; Dionne, Raymond; Freeman, Roy; Hansson, Per; Haroutounian, Simon; Arendt-Nielsen, Lars; Attal, Nadine; Baron, Ralf; Brell, Joanna; Bujanover, Shay; Burke, Laurie B.; Carr, Daniel; Chappell, Amy S.; Cowan, Penney; Etropolski, Mila; Fillingim, Roger B.; Gewandter, Jennifer S.; Katz, Nathaniel P.; Kopecky, Ernest A.; Markman, John D.; Nomikos, George; Porter, Linda; Rappaport, Bob A.; Rice, Andrew S. C.; Scavone, Joseph M.; Scholz, Joachim; Simon, Lee S.; Smith, Shannon M.; Tobias, Jeffrey; Tockarshewsky, Tina; Veasley, Christine; Versavel, Mark; Wasan, Ajay D.; Wen, Warren; Yarnitsky, David.

In: Pain, Vol. 157, No. 9, 2016, p. 1851-1871.

Research output: Contribution to journalReview articleResearchpeer-review

TY - JOUR

T1 - Patient phenotyping in clinical trials of chronic pain treatments

T2 - IMMPACT recommendations

AU - Edwards, Robert R.

AU - Dworkin, Robert H.

AU - Turk, Dennis C.

AU - Angst, Martin S.

AU - Dionne, Raymond

AU - Freeman, Roy

AU - Hansson, Per

AU - Haroutounian, Simon

AU - Arendt-Nielsen, Lars

AU - Attal, Nadine

AU - Baron, Ralf

AU - Brell, Joanna

AU - Bujanover, Shay

AU - Burke, Laurie B.

AU - Carr, Daniel

AU - Chappell, Amy S.

AU - Cowan, Penney

AU - Etropolski, Mila

AU - Fillingim, Roger B.

AU - Gewandter, Jennifer S.

AU - Katz, Nathaniel P.

AU - Kopecky, Ernest A.

AU - Markman, John D.

AU - Nomikos, George

AU - Porter, Linda

AU - Rappaport, Bob A.

AU - Rice, Andrew S. C.

AU - Scavone, Joseph M.

AU - Scholz, Joachim

AU - Simon, Lee S.

AU - Smith, Shannon M.

AU - Tobias, Jeffrey

AU - Tockarshewsky, Tina

AU - Veasley, Christine

AU - Versavel, Mark

AU - Wasan, Ajay D.

AU - Wen, Warren

AU - Yarnitsky, David

PY - 2016

Y1 - 2016

U2 - 10.1097/j.pain.0000000000000602

DO - 10.1097/j.pain.0000000000000602

M3 - Review article

VL - 157

SP - 1851

EP - 1871

JO - Pain

JF - Pain

SN - 0304-3959

IS - 9

ER -

Edwards RR, Dworkin RH, Turk DC, Angst MS, Dionne R, Freeman R et al. Patient phenotyping in clinical trials of chronic pain treatments: IMMPACT recommendations. Pain. 2016;157(9):1851-1871. https://doi.org/10.1097/j.pain.0000000000000602