Abstract
Several reports have suggested that peri-operative blood transfusion promotes tumour recurrence and death after surgery for cancer. We have studied the effect of transfusion in 156 patients operated on for prostatic cancer. A retrospective review was made of the clinical, histopathological and transfusion data in their hospital records. Sixty patients received blood transfusions and 96 did not. The 5-year prostatic cancer specific survival rate was 0.56 in the transfused patients and 0.69 in the non-transfused group. The transfused patients had a higher prevalence of risk factors than did the non-transfused. When the differences in risk factors were accounted for by Cox regression analysis, peri-operative blood transfusion reduced the prostatic cancer death intensity by 36%. The study does not support the hypothesis that blood transfusion promotes recurrence following surgery for prostatic cancer.
| Original language | English |
|---|---|
| Journal | B J U International (Print) |
| Volume | 68 |
| Issue number | 6 |
| Pages (from-to) | 608-11 |
| Number of pages | 4 |
| ISSN | 0007-1331 |
| Publication status | Published - Dec 1991 |
| Externally published | Yes |
Keywords
- Aged
- Aged, 80 and over
- Blood Transfusion
- Humans
- Male
- Middle Aged
- Neoplasm Recurrence, Local
- Prospective Studies
- Prostate
- Prostatic Neoplasms
- Retrospective Studies
- Risk Factors
- Surgical Procedures, Operative
- Survival Rate