Periprocedural complications and one-year outcomes after catheter ablation for treatment of atrial fibrillation in elderly patients: a nationwide Danish cohort study

Jesper Nielsen, Kristian Hay Kragholm*, Sofie Brix Christensen, Arne Johannessen, Christian Torp-Pedersen, Steen Buus Kristiansen, Peter Karl Jacobsen, Peter Steen Hansen, Mogens Stig Djurhus, Christoffer Polcwiartek, Peter Søgaard, Anna Margrethe Thøgersen, Uffe Jakob Ortved Gang, Ole Dan Jørgensen, Filip Lyng Lindgren, Sam Riahi

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

3 Citations (Scopus)

Abstract

OBJECTIVES: To investigate complications within 30-days following first-time ablation for atrial fibrillation (AF), including a composite of cardiac tamponade, hematoma requiring intervention, stroke or death, in patients ≥ 75 years of age, compared to patients aged 65-74 years. In addition, one-year all-cause mortality and AF relapse were compared.

METHODS & RESULTS: All patients receiving their first catheter ablation for AF between 2012 and 2016 were identified using Danish nationwide registries. Patients aged 65-74 years served as the reference group for patients ≥ 75 years. Relapse of AF within one year was defined as cardioversion following a three-month blanking period, re-ablation or confirmed relapse within follow-up. The composite complication outcome did not differ between the two age groups, with 39/1554 (2.8%) in patients 65-74 years of age, versus 5/199 (2.5%) in older patients (adjusted HR = 0.94), 95% CI: 0.37-2.39, P = 0.896). Patients ≥ 75 years or older had no increased hazard of death within 30 days after the procedure, with an incidence of 3/1554 (0.2%) in younger patients and 2/199 (1.0%) in patients ≥ 75 years of age (adjusted HR = 4.71, 95% CI: 0.78-28.40, P = 0.091). There was no difference in relapse of AF after one year between age groups (≥ 75 years adjusted HR = 1.00, 95% CI: 0.78-1.26, P = 0.969).

CONCLUSION: In patients ≥ 75 years of age selected for catheter ablation for AF, the incidence of periprocedural complications, as well as one-year freedom from AF showed no statistical difference, when compared to patients 65-74 years of age.

Original languageEnglish
JournalJournal of geriatric cardiology : JGC
Volume18
Issue number11
Pages (from-to)897-907
Number of pages11
ISSN1671-5411
DOIs
Publication statusPublished - 28 Nov 2021

Bibliographical note

Copyright and License information: Journal of Geriatric Cardiology 2021.

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