Potassium homoeostasis and pathophysiology of hyperkalaemia

Keld Per Kjeldsen; Thomas Andersen Schmidt

doi:10.1093/eurheartj/suy033

Potassium homoeostasis and pathophysiology of hyperkalaemia

Keld Per Kjeldsen, Thomas Andersen Schmidt

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

Determination of potassium level is one of the most frequent laboratory tests in clinical medicine. Hyperkalaemia is defined as a potassium level >5.0 mmol/L and is one of the most clinically important electrolyte abnormalities, because it may cause dangerous cardiac arrhythmia and sudden cardiac death. Here, we review methodological challenges in the determination of potassium levels, important clinical aspects of the potassium homoeostasis as well as of the pathophysiology of hyperkalaemia.

Original language	English
Journal	European Heart Journal Supplements
Volume	21
Issue number	Suppl A
Pages (from-to)	A2-A5
ISSN	1554-2815
DOIs	https://doi.org/10.1093/eurheartj/suy033
Publication status	Published - 26 Feb 2019

Keywords

Arrhythmia
Hyperkalaemia
Na,K-ATPase
Na,K-Pumps
Plasma potassium
Potassium
Potassium homoeostasis
Serum potassium
Sodium, Potassium-Adenosinetriphosphatase
Sudden cardiac death

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10.1093/eurheartj/suy033Licence: CC BY-NC 4.0

Open Access articleFinal published version, 144 KBLicence: CC BY-NC 4.0

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AB - Determination of potassium level is one of the most frequent laboratory tests in clinical medicine. Hyperkalaemia is defined as a potassium level >5.0 mmol/L and is one of the most clinically important electrolyte abnormalities, because it may cause dangerous cardiac arrhythmia and sudden cardiac death. Here, we review methodological challenges in the determination of potassium levels, important clinical aspects of the potassium homoeostasis as well as of the pathophysiology of hyperkalaemia.

KW - Arrhythmia

KW - Hyperkalaemia

KW - Na,K-ATPase

KW - Na,K-Pumps

KW - Plasma potassium

KW - Potassium

KW - Potassium homoeostasis

KW - Serum potassium

KW - Sodium, Potassium-Adenosinetriphosphatase

KW - Sudden cardiac death

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DO - 10.1093/eurheartj/suy033

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VL - 21

SP - A2-A5

JO - European Heart Journal Supplements

JF - European Heart Journal Supplements

IS - Suppl A

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Potassium homoeostasis and pathophysiology of hyperkalaemia

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Keywords

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