Abstract
Background: Epiphysiodesis made with RFA has resulted,
in animal models, an effective procedure that
disrupts the growth plate and induces LLD.
This procedure involves an increase of
temperature (>92°C) of the targeted region
causing thermal damage. To our knowledge,
no study that investigates the effect of this
procedure in the adjacent joint articular
cartilage has been reported
Purpose / Aim of Study: Proof of concept that epiphysiodesis made
with RFA is a safe procedure that disrupts
the growth plate without damaging the
adjacent joint articular cartilage
Materials and Methods: RFA Epiphysiodesis RFA was done for 8
minutes in vivo in 40 growing pig tibia physis.
In addition, three tibiae were ablated for 16
minutes, and three more for 24 minutes. As
a damage reference, 6 tibiae were ablated
on the joint articular cartilage for 8 minutes.
MRI was done ex vivo after the procedure to
evaluate the joint articular cartilage in all
samples using T1-weighted, T2-weighted
and water content sequences under a 1.5 T
magnetic field
Findings / Results: The intentionally-damaged articular cartilage
showed intensity changes on the MR. This
images were used as reference for damage.
We found no evidence of articular cartilage
damage on the 40 8 mins procedures. The
tibiae ablated for 16 mins showed a larger
lesion on the physis but the articular joint
cartilage was intact. No articular cartilage
damage was found on the tibiae ablated for
16 mins
Conclusions: Epiphysiodesis using RFA is safe for the
adjacent articular joint cartilage. This
study resembles possible results of RFA
epiphysiodesis on humans. Previous
studies suggest that an 8 min ablation is
enough to disrupt the growth plate. This
study shows that RFA can be done
safely in the growing physis even on
triple-long procedures. It is important to
highlight that all this evidence was
obtained on an animal model
in animal models, an effective procedure that
disrupts the growth plate and induces LLD.
This procedure involves an increase of
temperature (>92°C) of the targeted region
causing thermal damage. To our knowledge,
no study that investigates the effect of this
procedure in the adjacent joint articular
cartilage has been reported
Purpose / Aim of Study: Proof of concept that epiphysiodesis made
with RFA is a safe procedure that disrupts
the growth plate without damaging the
adjacent joint articular cartilage
Materials and Methods: RFA Epiphysiodesis RFA was done for 8
minutes in vivo in 40 growing pig tibia physis.
In addition, three tibiae were ablated for 16
minutes, and three more for 24 minutes. As
a damage reference, 6 tibiae were ablated
on the joint articular cartilage for 8 minutes.
MRI was done ex vivo after the procedure to
evaluate the joint articular cartilage in all
samples using T1-weighted, T2-weighted
and water content sequences under a 1.5 T
magnetic field
Findings / Results: The intentionally-damaged articular cartilage
showed intensity changes on the MR. This
images were used as reference for damage.
We found no evidence of articular cartilage
damage on the 40 8 mins procedures. The
tibiae ablated for 16 mins showed a larger
lesion on the physis but the articular joint
cartilage was intact. No articular cartilage
damage was found on the tibiae ablated for
16 mins
Conclusions: Epiphysiodesis using RFA is safe for the
adjacent articular joint cartilage. This
study resembles possible results of RFA
epiphysiodesis on humans. Previous
studies suggest that an 8 min ablation is
enough to disrupt the growth plate. This
study shows that RFA can be done
safely in the growing physis even on
triple-long procedures. It is important to
highlight that all this evidence was
obtained on an animal model
| Original language | English |
|---|---|
| Publication date | 2013 |
| Publication status | Published - 2013 |
| Externally published | Yes |
| Event | DOS Kongressen 2013 - Radisson Blu Scandinavia Hotel, Køvenhavn, Copenhagen, Denmark Duration: 23 Oct 2013 → 25 Oct 2013 |
Conference
| Conference | DOS Kongressen 2013 |
|---|---|
| Location | Radisson Blu Scandinavia Hotel, Køvenhavn |
| Country/Territory | Denmark |
| City | Copenhagen |
| Period | 23/10/2013 → 25/10/2013 |