Pressure Myography to Study the Function and Structure of Isolated Small Arteries

Olav L Schjørring, Rune Carlsson, Ulf Simonsen

Research output: Contribution to book/anthology/report/conference proceedingBook chapterResearchpeer-review

13 Citations (Scopus)

Abstract

Small arteries play an important role in regulation of peripheral resistance and organ perfusion. Here we describe a series of methods allowing measurements in pressurized segments of small arteries from the systemic and coronary circulation of mice as well as other species. The pressure myography techniques described include measurements of wall structure, wall stress, strain, and myogenic tone. The pressurized perfused small arteries also allow evaluation of responses to increases in pressure, flow, and drugs, where the main readout is changes in vascular diameter.

Original languageEnglish
Title of host publicationMethods In Mouse Atherosclerosis
EditorsVicente Andrés, Beatriz Dorado
Number of pages19
PublisherSpringer Science+Business Media
Publication date2015
Pages277-295
Chapter19
ISBN (Print)978-1-4939-2928-3
ISBN (Electronic)978-1-4939-2929-0
DOIs
Publication statusPublished - 2015
SeriesMethods in Molecular Biology
Number1339
ISSN1064-3745

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