Psychosocial, sexual, reproductive and menopausal health in women with and without HIV in a high-income setting

Ditte Scofield*, Nina Weis, Mikael Andersson, Merete Storgaard, Gitte Pedersen, Isik S. Johansen, Terese L. Katzenstein, Christian Graugaard, Morten Frisch, Ellen Moseholm

*Corresponding author for this work

Research output: Contribution to journalLetterpeer-review

2 Citations (Scopus)


OBJECTIVES: To investigate psychosocial, sexual, reproductive and menopausal health in women with HIV (WWH) compared to women without HIV (WWOH) in Denmark.

DESIGN: A nationwide cross-sectional study.

METHODS: Data was retrieved from the SHARE study, a Danish nationwide cross-sectional survey examining psychosocial, sexual and reproductive health in people with HIV. Data from WWH, collected in 2021-2022, was matched 1:10 on age to a comparison group of WWOH from the nationally representative cohort study Project SEXUS. Associations between HIV status and psychosocial and sexual health outcomes were assessed by adjusted odds ratios (aOR) with 95% confidence intervals (95% CIs) obtained in logistic regression analyses controlling for potential confounding variables. The severity of menopausal symptoms in WWH was compared to published reference norms.

RESULTS: Among 144 WWH and 1440 WWOH, recurrent loneliness was significantly more common among WWH (aOR 2.22 [95% CI: 1.25-3.96]), and WWH had significantly fewer children and close friends (aOR 0.52 [95% CI: 0.28-0.96] for 3-9 vs. 0-2 close friends). Symptoms of anxiety and depression did not differ between groups. Lack of sexual desire (aOR 2.90 [95% CI: 1.29-6.50]), low FSFI-6 score indicating sexual dysfunction (aOR 3.40 [95% CI: 1.33-8.69]), lubrication dysfunction (aOR 8.24 [95% CI: 2.83-24.00]) and genital pain dysfunction (aOR 5.13 [95% CI: 1.26-20.86]) were significantly more common in WWH compared to WWOH. No differences were seen in menopausal characteristics.

CONCLUSIONS: WWH in Denmark have fewer children and close friends, and more often report recurrent loneliness, lacking sexual desire and sexual dysfunction compared to WWOH. No differences were evident in menopausal characteristics.

Original languageEnglish
Issue number8
Pages (from-to)1315-1322
Number of pages8
Publication statusPublished - 1 Jul 2023

Bibliographical note

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.


  • HIV
  • cross-sectional
  • loneliness
  • menopause
  • mental health
  • sexual health
  • women


Dive into the research topics of 'Psychosocial, sexual, reproductive and menopausal health in women with and without HIV in a high-income setting'. Together they form a unique fingerprint.

Cite this