Abstract
A 68-kDa protein that binds to the murine dendritic cell-specific monoclonal antibody M342 was purified and its amino acid sequence was partially determined. Corresponding cDNA clones code for a protein that is closely related to a 62-kDa human protein (p62) that associates with the Ras GTPase-activating protein, p120 GAP, suggesting that p62 may have a dendritic cell-specific function or that an M342 cross-reactive epitope may exist on the murine p62 molecule.
Original language | English |
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Journal | Gene |
Volume | 158 |
Issue number | 2 |
Pages (from-to) | 307-8 |
Number of pages | 2 |
ISSN | 0378-1119 |
Publication status | Published - 9 Jun 1995 |
Externally published | Yes |
Keywords
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Base Sequence
- DNA, Complementary
- DNA-Binding Proteins
- Dendritic Cells
- Epitopes
- GTPase-Activating Proteins
- Gene Library
- Humans
- Mice
- Molecular Sequence Data
- Phosphoproteins
- Proteins
- RNA-Binding Proteins
- Sequence Analysis
- Sequence Homology, Amino Acid
- ras GTPase-Activating Proteins
- ras Proteins
- Comparative Study
- Journal Article
- Research Support, Non-U.S. Gov't