Purification and cDNA sequence of a murine protein homologous to the human p62 tyrosine phosphoprotein that associates with the Ras GTPase-activating protein p120 GAP

R Agger, P Freimuth

Research output: Contribution to journalJournal articleResearchpeer-review

3 Citations (Scopus)

Abstract

A 68-kDa protein that binds to the murine dendritic cell-specific monoclonal antibody M342 was purified and its amino acid sequence was partially determined. Corresponding cDNA clones code for a protein that is closely related to a 62-kDa human protein (p62) that associates with the Ras GTPase-activating protein, p120 GAP, suggesting that p62 may have a dendritic cell-specific function or that an M342 cross-reactive epitope may exist on the murine p62 molecule.

Original languageEnglish
JournalGene
Volume158
Issue number2
Pages (from-to)307-8
Number of pages2
ISSN0378-1119
Publication statusPublished - 9 Jun 1995
Externally publishedYes

Keywords

  • Amino Acid Sequence
  • Animals
  • Antibodies, Monoclonal
  • Base Sequence
  • DNA, Complementary
  • DNA-Binding Proteins
  • Dendritic Cells
  • Epitopes
  • GTPase-Activating Proteins
  • Gene Library
  • Humans
  • Mice
  • Molecular Sequence Data
  • Phosphoproteins
  • Proteins
  • RNA-Binding Proteins
  • Sequence Analysis
  • Sequence Homology, Amino Acid
  • ras GTPase-Activating Proteins
  • ras Proteins
  • Comparative Study
  • Journal Article
  • Research Support, Non-U.S. Gov't

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