Quick guide to secondary metabolites from Apiospora and Arthrinium

Marie Lund Overgaard, Trine Aalborg, Emil Juel Zeuner, Klaus Ringsborg Westphal, Frederik Andersen Lau, Vibeke Steenfeldt Nielsen, Kasper Buhl Carstensen, Emil Alsholm Hundebøll, Tia Amalie Rosenkrantz Westermann, Gustav Gaardsholt Rathsach, Jens Laurids Sørensen, Jens Frisvad, Reinhard Wimmer, Teis Esben Sondergaard*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)

Abstract

Apiospora and Arthrinium have undergone a period of upheaval with disparate phylogenic affiliation during the past ten years. Recently, they were divided into two separate clades with the majority being Apiospora and several species changing genus from Arthrinum to Apiospora. The first genome annotation became available in 2020, and the potential for novel secondary metabolite production appears very high in these yet unexplored genera compared to other more famous filamentous fungi. In this review, we present the current state of knowledge of 269 secondary metabolites isolated from the two fungal genera combined and highlight some of the compounds with known biological or toxic effects.
Original languageEnglish
Article number100288
JournalFungal Biology Reviews
Volume43
ISSN1749-4613
DOIs
Publication statusPublished - Mar 2023

Keywords

  • Apiospora
  • Arthrinium
  • Non-ribosomal peptide
  • Polyketide
  • Secondary metabolism
  • Terpenoid

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