Recovery of renal function succeeding stem cell transplant: a case of C3 Glomerulonephiritis secondary to monoclonal gammopathy

Camilla Aakjær Andersen, Niels Marcussen, Jon Waarst Gregersen

Research output: Contribution to journalJournal articleResearchpeer-review

3 Citations (Scopus)

Abstract

Membranoproliferative glomerulonephritis (MPGN) and C3 glomerulonephritis (C3 GN) can be secondary to monoclonal gammopathy and multiple myeloma. MPGN Type 1 is caused by activation of the classical pathway by immune complex formation, and C3 GN results from abnormalities in the alternative pathway of complement. In previously reported cases of MPGN and C3 GN secondary to monoclonal gammopathy/multiple myeloma, renal outcome has been poor. Here, we present the first patient, to our knowledge, who showed full renal recovery and normalization of the complement system after chemotherapy and stem cell transplantation.

Original languageEnglish
JournalClinical Kidney Journal
Volume6
Issue number6
Pages (from-to)639-42
Number of pages4
ISSN2048-8505
DOIs
Publication statusPublished - Dec 2013
Externally publishedYes

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