TY - JOUR
T1 - Recurrent atrial flutter ablation and incidence of atrial fibrillation ablation after first-time ablation for typical atrial flutter
T2 - A nation-wide Danish cohort study
AU - Giehm-Reese, Mikkel
AU - Kronborg, Mads Brix
AU - Lukac, Peter
AU - Kristiansen, Steen Buus
AU - Nielsen, Jan Møller
AU - Johannessen, Arne
AU - Jacobsen, Peter Karl
AU - Djurhuus, Mogens Stig
AU - Riahi, Sam
AU - Hansen, Peter Steen
AU - Nielsen, Jens Cosedis
PY - 2020/1
Y1 - 2020/1
N2 - BACKGROUND: Cavo tricuspid isthmus ablation (CTIA) is considered an effective first-line treatment for typical atrial flutter (AFL). However, many patients develop atrial fibrillation (AF) after successful CTIA. Knowledge about recurrent arrhythmia after CTIA mainly comes from small cohort studies with limited follow-up.OBJECTIVE: To describe incidences of re-ablation for AFL and ablation for AF after first-time CTIA in a nation-wide cohort.METHODS: In the Danish National Ablation Registry we identified patients undergoing first-time CTIA during 2010-2016. Subsequent CTIA and AF-ablation procedures were identified until March 1st, 2018. We collected information on patient comorbidities in the Danish National Patient Registry.RESULTS: We identified 2409 patients undergoing first-time CTIA. Median age was 66 (IQR 58-72) years, 1952 (81%) were men, and 78 (3%) patients had a history of previous ablation for AF. Acute procedural success was achieved in 2288 (95%) patients. During mean follow-up of 4.0±1.7years, 242 (10%) patients underwent CTI re-ablation and 326 (13.5%) underwent ablation for AF. Baseline characteristics associated with CTI re-ablation included prolonged procedural time, unsuccessful index CTIA, age <75years and CHA2DS2-VASc score <2. Hypertension, history of AF-ablation, age <65years use of a contact force sensing catheter and CHA2DS2-VASc score <2 were associated with later ablation for AF.CONCLUSION: In a nation-wide cohort undergoing first-time CTIA for AFL, 10% of patients underwent CTI re-ablation and 13.5% ablation for AF during mean follow-up of 4.0±1.7years. Probability of a second procedure was higher in younger patients with less comorbidities.
AB - BACKGROUND: Cavo tricuspid isthmus ablation (CTIA) is considered an effective first-line treatment for typical atrial flutter (AFL). However, many patients develop atrial fibrillation (AF) after successful CTIA. Knowledge about recurrent arrhythmia after CTIA mainly comes from small cohort studies with limited follow-up.OBJECTIVE: To describe incidences of re-ablation for AFL and ablation for AF after first-time CTIA in a nation-wide cohort.METHODS: In the Danish National Ablation Registry we identified patients undergoing first-time CTIA during 2010-2016. Subsequent CTIA and AF-ablation procedures were identified until March 1st, 2018. We collected information on patient comorbidities in the Danish National Patient Registry.RESULTS: We identified 2409 patients undergoing first-time CTIA. Median age was 66 (IQR 58-72) years, 1952 (81%) were men, and 78 (3%) patients had a history of previous ablation for AF. Acute procedural success was achieved in 2288 (95%) patients. During mean follow-up of 4.0±1.7years, 242 (10%) patients underwent CTI re-ablation and 326 (13.5%) underwent ablation for AF. Baseline characteristics associated with CTI re-ablation included prolonged procedural time, unsuccessful index CTIA, age <75years and CHA2DS2-VASc score <2. Hypertension, history of AF-ablation, age <65years use of a contact force sensing catheter and CHA2DS2-VASc score <2 were associated with later ablation for AF.CONCLUSION: In a nation-wide cohort undergoing first-time CTIA for AFL, 10% of patients underwent CTI re-ablation and 13.5% ablation for AF during mean follow-up of 4.0±1.7years. Probability of a second procedure was higher in younger patients with less comorbidities.
KW - Atrial flutter
KW - Catheter ablation
KW - New-onset atrial fibrillation
KW - Repeat ablation
UR - http://www.scopus.com/inward/record.url?scp=85077049798&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2019.07.077
DO - 10.1016/j.ijcard.2019.07.077
M3 - Journal article
C2 - 31521436
SN - 0167-5273
VL - 298
SP - 44
EP - 51
JO - International Journal of Cardiology
JF - International Journal of Cardiology
ER -