Middle ear pressure regulation: Compliant structures counterbalancing pressure changes

Research output: Book/ReportPh.D. thesisResearch

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Abstract

One of the most frequent otological diseases is otitis media with effusion. This condition consists of inflammatory changes within the middle ear, and accumulation of an under-atmospheric pressure. The consequences are often serious when the under-pressure persists for a long time, becoming chronic. In certain cases, the condition results in the formation of retraction pockets in the tympanic membrane, bone erosion, and cholesteatoma formation. This loss of structural integrity of the middle ear leads inevitably to hearing loss.
The treatment of chronic Otitis media with effusion requires often surgery. The success of surgical reconstruction depends on the restauration of the pressure balance between the middle ear and the ambient atmosphere. Therefore, the understanding of the basic mechanisms of the pressure regulation within the middle ear is essential.
The following work contributes evidence to the role of the main compliant structures of the middle ear, known to or hypothesized to influence the middle ear pressure.
Translated title of the contributionRegulering af mellemøretryk: Compliant strukturer med betydning ved trykændringer.
Original languageEnglish
PublisherAalborg Universitetsforlag
Number of pages71
ISBN (Electronic)978-87-7210-209-2
Publication statusPublished - 2018
SeriesAalborg Universitet. Det Sundhedsvidenskabelige Fakultet. Ph.D.-Serien
ISSN2246-1302

Bibliographical note

PhD supervisor:
Associate Professor, PhD, MD Michael Gaihede, Department of Otology, Head and Neck Surgery, Aalborg University Hospital, Department of Clinical Medicine
Aalborg University, Denmark

Assistant PhD supervisors:
Professor, MD Mogens Vyberg, Institute of Pathology, Aalborg University Hospital
Department of Clinical Medicine, Aalborg University, Denmark
Associate Professor, PhD, Allan Stensballe, Department of Health Science and Technology, Aalborg University, Denmark

Keywords

    Keywords

      Cite this

      Padurariu, S. (2018). Middle ear pressure regulation: Compliant structures counterbalancing pressure changes. Aalborg Universitetsforlag. Aalborg Universitet. Det Sundhedsvidenskabelige Fakultet. Ph.D.-Serien
      Padurariu, Simona. / Middle ear pressure regulation : Compliant structures counterbalancing pressure changes. Aalborg Universitetsforlag, 2018. 71 p. (Aalborg Universitet. Det Sundhedsvidenskabelige Fakultet. Ph.D.-Serien).
      @phdthesis{faf459c76599423b9cae248c6f3f3ef2,
      title = "Middle ear pressure regulation: Compliant structures counterbalancing pressure changes",
      abstract = "One of the most frequent otological diseases is otitis media with effusion. This condition consists of inflammatory changes within the middle ear, and accumulation of an under-atmospheric pressure. The consequences are often serious when the under-pressure persists for a long time, becoming chronic. In certain cases, the condition results in the formation of retraction pockets in the tympanic membrane, bone erosion, and cholesteatoma formation. This loss of structural integrity of the middle ear leads inevitably to hearing loss.The treatment of chronic Otitis media with effusion requires often surgery. The success of surgical reconstruction depends on the restauration of the pressure balance between the middle ear and the ambient atmosphere. Therefore, the understanding of the basic mechanisms of the pressure regulation within the middle ear is essential. The following work contributes evidence to the role of the main compliant structures of the middle ear, known to or hypothesized to influence the middle ear pressure.",
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      author = "Simona Padurariu",
      note = "PhD supervisor: Associate Professor, PhD, MD Michael Gaihede, Department of Otology, Head and Neck Surgery, Aalborg University Hospital, Department of Clinical Medicine Aalborg University, Denmark Assistant PhD supervisors: Professor, MD Mogens Vyberg, Institute of Pathology, Aalborg University Hospital Department of Clinical Medicine, Aalborg University, Denmark Associate Professor, PhD, Allan Stensballe, Department of Health Science and Technology, Aalborg University, Denmark",
      year = "2018",
      language = "English",
      publisher = "Aalborg Universitetsforlag",

      }

      Padurariu, S 2018, Middle ear pressure regulation: Compliant structures counterbalancing pressure changes. Aalborg Universitet. Det Sundhedsvidenskabelige Fakultet. Ph.D.-Serien, Aalborg Universitetsforlag.

      Middle ear pressure regulation : Compliant structures counterbalancing pressure changes. / Padurariu, Simona.

      Aalborg Universitetsforlag, 2018. 71 p.

      Research output: Book/ReportPh.D. thesisResearch

      TY - BOOK

      T1 - Middle ear pressure regulation

      T2 - Compliant structures counterbalancing pressure changes

      AU - Padurariu, Simona

      N1 - PhD supervisor: Associate Professor, PhD, MD Michael Gaihede, Department of Otology, Head and Neck Surgery, Aalborg University Hospital, Department of Clinical Medicine Aalborg University, Denmark Assistant PhD supervisors: Professor, MD Mogens Vyberg, Institute of Pathology, Aalborg University Hospital Department of Clinical Medicine, Aalborg University, Denmark Associate Professor, PhD, Allan Stensballe, Department of Health Science and Technology, Aalborg University, Denmark

      PY - 2018

      Y1 - 2018

      N2 - One of the most frequent otological diseases is otitis media with effusion. This condition consists of inflammatory changes within the middle ear, and accumulation of an under-atmospheric pressure. The consequences are often serious when the under-pressure persists for a long time, becoming chronic. In certain cases, the condition results in the formation of retraction pockets in the tympanic membrane, bone erosion, and cholesteatoma formation. This loss of structural integrity of the middle ear leads inevitably to hearing loss.The treatment of chronic Otitis media with effusion requires often surgery. The success of surgical reconstruction depends on the restauration of the pressure balance between the middle ear and the ambient atmosphere. Therefore, the understanding of the basic mechanisms of the pressure regulation within the middle ear is essential. The following work contributes evidence to the role of the main compliant structures of the middle ear, known to or hypothesized to influence the middle ear pressure.

      AB - One of the most frequent otological diseases is otitis media with effusion. This condition consists of inflammatory changes within the middle ear, and accumulation of an under-atmospheric pressure. The consequences are often serious when the under-pressure persists for a long time, becoming chronic. In certain cases, the condition results in the formation of retraction pockets in the tympanic membrane, bone erosion, and cholesteatoma formation. This loss of structural integrity of the middle ear leads inevitably to hearing loss.The treatment of chronic Otitis media with effusion requires often surgery. The success of surgical reconstruction depends on the restauration of the pressure balance between the middle ear and the ambient atmosphere. Therefore, the understanding of the basic mechanisms of the pressure regulation within the middle ear is essential. The following work contributes evidence to the role of the main compliant structures of the middle ear, known to or hypothesized to influence the middle ear pressure.

      KW - mellemøre fysiologi

      KW - mellemøre betændelse

      M3 - Ph.D. thesis

      BT - Middle ear pressure regulation

      PB - Aalborg Universitetsforlag

      ER -

      Padurariu S. Middle ear pressure regulation: Compliant structures counterbalancing pressure changes. Aalborg Universitetsforlag, 2018. 71 p. (Aalborg Universitet. Det Sundhedsvidenskabelige Fakultet. Ph.D.-Serien).