Safety of Intravenous and Inhalation Anesthetics

Luiz Fernando Ferrari, Lars Arendt-Nielsen

Research output: Contribution to book/anthology/report/conference proceedingBook chapterResearchpeer-review


Here is presented, in chronological order, the studies that established the standards and determined the parameters currently considered for the safe use of anesthetic agents administered by intravenous or inhalation routes. The methods used in the experimental settings, as well as the modifications in the protocols to adapt to different clinical conditions, are described and discussed; The pharmacological criteria and the impact of these anesthetics on the cardiovascular and pulmonary systems are highlighted. However, additional information regarding the mechanisms of action of such agents is still needed, which would improve their use in terms of safety and efficacy.
Original languageEnglish
Title of host publicationDrug Discovery and Evaluation : Safety and Pharmacokinetic Assays
EditorsFranz J. Hock, Michael R. Gralinski, Michael K. Pugsley
Publication date2 Dec 2022
ISBN (Print)978-3-030-73317-9
ISBN (Electronic)978-3-030-73317-9
Publication statusPublished - 2 Dec 2022


  • Intravenous anesthetics
  • Inhalation anesthetics
  • Anesthetics safety
  • Anesthetic safety assessment
  • Anesthetic Potency
  • Minimum Alveolar Concentration


Dive into the research topics of 'Safety of Intravenous and Inhalation Anesthetics'. Together they form a unique fingerprint.

Cite this