Safety of Intravenous and Inhalation Anesthetics

Luiz Fernando Ferrari; Lars Arendt-Nielsen

doi:10.1007/978-3-030-73317-9_68-1

Safety of Intravenous and Inhalation Anesthetics

Luiz Fernando Ferrari, Lars Arendt-Nielsen

Research output: Contribution to book/anthology/report/conference proceeding › Book chapter › Research › peer-review

Abstract

Here is presented, in chronological order, the studies that established the standards and determined the parameters currently considered for the safe use of anesthetic agents administered by intravenous or inhalation routes. The methods used in the experimental settings, as well as the modifications in the protocols to adapt to different clinical conditions, are described and discussed; The pharmacological criteria and the impact of these anesthetics on the cardiovascular and pulmonary systems are highlighted. However, additional information regarding the mechanisms of action of such agents is still needed, which would improve their use in terms of safety and efficacy.

Original language	English
Title of host publication	Drug Discovery and Evaluation : Safety and Pharmacokinetic Assays
Editors	Franz J. Hock, Michael R. Gralinski, Michael K. Pugsley
Publisher	Springer
Publication date	2 Dec 2022
Pages	1-9
ISBN (Print)	978-3-030-73317-9
ISBN (Electronic)	978-3-030-73317-9
DOIs	https://doi.org/10.1007/978-3-030-73317-9_68-1
Publication status	Published - 2 Dec 2022

Keywords

Intravenous anesthetics
Inhalation anesthetics
Anesthetics safety
Anesthetic safety assessment
Anesthetic Potency
Minimum Alveolar Concentration

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10.1007/978-3-030-73317-9_68-1

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Safety of Intravenous and Inhalation Anesthetics. / Ferrari, Luiz Fernando; Arendt-Nielsen, Lars.
Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. ed. / Franz J. Hock; Michael R. Gralinski; Michael K. Pugsley. Springer, 2022. p. 1-9.

Research output: Contribution to book/anthology/report/conference proceeding › Book chapter › Research › peer-review

TY - CHAP

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KW - Anesthetic safety assessment

KW - Anesthetic Potency

KW - Minimum Alveolar Concentration

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Safety of Intravenous and Inhalation Anesthetics

Abstract

Keywords

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