Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021

Peter Willeit; Benoît Bernar; Christoph Zurl; Mariam Al-Rawi; Andrea Berghold; David Bernhard; Wegene Borena; Christian Doppler; Reinhold Kerbl; Alwin Köhler; Robert Krause; Bernd Lamprecht; Johannes Pröll; Hannes Schmidt; Ivo Steinmetz; Evelyn Stelzl; Heribert Stoiber; Dorothee Von Laer; Johannes Zuber; Thomas Müller; Volker Strenger; Michael Wagner

doi:10.2807/1560-7917.ES.2021.26.34.2100797

Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021

Peter Willeit, Benoît Bernar, Christoph Zurl, Mariam Al-Rawi, Andrea Berghold, David Bernhard, Wegene Borena, Christian Doppler, Reinhold Kerbl, Alwin Köhler, Robert Krause, Bernd Lamprecht, Johannes Pröll, Hannes Schmidt, Ivo Steinmetz, Evelyn Stelzl, Heribert Stoiber, Dorothee Von Laer, Johannes Zuber, Thomas MüllerVolker Strenger^*, Michael Wagner

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

27 Downloads (Pure)

Abstract

This study evaluates the performance of the antigenbased anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1-8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and noninfected individuals mainly tested negative (very high specificity).

Original language	English
Article number	2100797
Journal	Eurosurveillance
Volume	26
Issue number	34
ISSN	1025-496X
DOIs	https://doi.org/10.2807/1560-7917.ES.2021.26.34.2100797
Publication status	Published - 26 Aug 2021

Bibliographical note

Publisher Copyright:
© 2021 European Centre for Disease Prevention and Control (ECDC). All rights reserved.

Access to Document

10.2807/1560-7917.ES.2021.26.34.2100797

eurosurv-26-34-1Final published version, 666 KBLicence: CC BY 4.0

AUB Link

Search for the material in Aalborg University Library's search engine

Cite this

Willeit, P., Bernar, B., Zurl, C., Al-Rawi, M., Berghold, A., Bernhard, D., Borena, W., Doppler, C., Kerbl, R., Köhler, A., Krause, R., Lamprecht, B., Pröll, J., Schmidt, H., Steinmetz, I., Stelzl, E., Stoiber, H., Von Laer, D., Zuber, J., ... Wagner, M. (2021). Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021. Eurosurveillance, 26(34), Article 2100797. https://doi.org/10.2807/1560-7917.ES.2021.26.34.2100797

@article{e2f3fd257edd45818fd9f35da92fdebd,

title = "Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021",

abstract = "This study evaluates the performance of the antigenbased anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1-8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and noninfected individuals mainly tested negative (very high specificity).",

author = "Peter Willeit and Beno{\^i}t Bernar and Christoph Zurl and Mariam Al-Rawi and Andrea Berghold and David Bernhard and Wegene Borena and Christian Doppler and Reinhold Kerbl and Alwin K{\"o}hler and Robert Krause and Bernd Lamprecht and Johannes Pr{\"o}ll and Hannes Schmidt and Ivo Steinmetz and Evelyn Stelzl and Heribert Stoiber and {Von Laer}, Dorothee and Johannes Zuber and Thomas M{\"u}ller and Volker Strenger and Michael Wagner",

year = "2021",

month = aug,

day = "26",

doi = "10.2807/1560-7917.ES.2021.26.34.2100797",

language = "English",

volume = "26",

journal = "Eurosurveillance",

issn = "1025-496X",

publisher = "Centre Europeen pour la Surveillance Epidemiologique du SIDA",

number = "34",

}

Willeit, P, Bernar, B, Zurl, C, Al-Rawi, M, Berghold, A, Bernhard, D, Borena, W, Doppler, C, Kerbl, R, Köhler, A, Krause, R, Lamprecht, B, Pröll, J, Schmidt, H, Steinmetz, I, Stelzl, E, Stoiber, H, Von Laer, D, Zuber, J, Müller, T, Strenger, V & Wagner, M 2021, 'Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021', Eurosurveillance, vol. 26, no. 34, 2100797. https://doi.org/10.2807/1560-7917.ES.2021.26.34.2100797

TY - JOUR

T1 - Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021

AU - Willeit, Peter

AU - Bernar, Benoît

AU - Zurl, Christoph

AU - Al-Rawi, Mariam

AU - Berghold, Andrea

AU - Bernhard, David

AU - Borena, Wegene

AU - Doppler, Christian

AU - Kerbl, Reinhold

AU - Köhler, Alwin

AU - Krause, Robert

AU - Lamprecht, Bernd

AU - Pröll, Johannes

AU - Schmidt, Hannes

AU - Steinmetz, Ivo

AU - Stelzl, Evelyn

AU - Stoiber, Heribert

AU - Von Laer, Dorothee

AU - Zuber, Johannes

AU - Müller, Thomas

AU - Strenger, Volker

AU - Wagner, Michael

PY - 2021/8/26

Y1 - 2021/8/26

N2 - This study evaluates the performance of the antigenbased anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1-8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and noninfected individuals mainly tested negative (very high specificity).

AB - This study evaluates the performance of the antigenbased anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1-8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and noninfected individuals mainly tested negative (very high specificity).

UR - http://www.scopus.com/inward/record.url?scp=85114832329&partnerID=8YFLogxK

U2 - 10.2807/1560-7917.ES.2021.26.34.2100797

DO - 10.2807/1560-7917.ES.2021.26.34.2100797

M3 - Journal article

C2 - 34448449

AN - SCOPUS:85114832329

SN - 1025-496X

VL - 26

JO - Eurosurveillance

JF - Eurosurveillance

IS - 34

M1 - 2100797

ER -

Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021

Abstract

Bibliographical note

Access to Document

AUB Link

Other files and links

Fingerprint

Cite this