Severe and ChRonic Atopic dermatitis Treatment CoHort (SCRATCH): A Danish Real-world Evidence Atopic Dermatitis Treatment Registry

Henrik H. P. Larsen, Ida Vittrup, Iben F. Ruge, Jesper Elberling, Lone Skov, Kristina Ibler, Gregor B. E. Jemec, Charlotte G. Mortz, Rasmus O. Bach, Carsten Bindslev-Jensen, Maiken G. Dalager, Tove Agner, Mette Deleuran, Christian Vestergaard, Jacob Thyssen*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

7 Citations (Scopus)
116 Downloads (Pure)

Abstract

Data from real-world use of new systemic treatments in atopic dermatitis (AD) is important for assessing safety and efficacy. The aim of this study is to describe the baseline characteristics of adult patients with moderate-to-severe AD enrolled in the Danish nationwide Severe and ChRonic Atopic dermatitis Treatment CoHort (SCRATCH) database, between October 2017 and August 2021. A total of 282 adult patients were included. Most (62%) were men, the median age at baseline was 43 years (interquartile range (IQR) 29-54 years), and median age at onset of AD was 1 year (IQR 0-6 years). The median Eczema Area and Severity Index at treatment initiation was 19.1 (IQR 11.9-25.7); median Patient Oriented Eczema Measure 21.0 (IQR 16.0-25.0); median Dermatology Life Quality Index 13.0 (IQR 7.0-19.0); and median itch and sleep numerical rating scale scores 8.0 (IQR 6.0-9.0) and 6.0 (IQR 4.0-8.0). Differences were found between the sexes. This registry will provide a source for future efficacy and safety studies.

Original languageEnglish
Article numberadv00760
JournalActa Dermato-Venereologica
Volume102
ISSN0001-5555
DOIs
Publication statusPublished - 24 Aug 2022

Keywords

  • atopic dermatitis
  • baricitinib
  • dupilumab
  • real-world
  • registry
  • treatment

Fingerprint

Dive into the research topics of 'Severe and ChRonic Atopic dermatitis Treatment CoHort (SCRATCH): A Danish Real-world Evidence Atopic Dermatitis Treatment Registry'. Together they form a unique fingerprint.

Cite this