Small atrial septal defects are associated with psychiatric diagnoses, emotional distress, and lower educational levels

Sebastian Udholm, Camilla Nyboe, Thomas Meinertz Dantoft, Torben Jørgensen, Charlotte U Rask, Vibeke E Hjortdal

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

OBJECTIVE: For the first time, we wish to assess the psychiatric burden in adult patients living with small, unrepaired atrial septal defects (ASD) using register-based data, combined with self-reported measures on levels emotional distress and educational status.

DESIGN: A descriptive study using both the unique Danish registries and validated psychiatric questionnaires and scales, including: The Symptom Checklist, Whiteley-7, and Brief Illness Perception Questionnaire.

PATIENTS: Adult patients with small, unrepaired ASD, diagnosed between 1953 and 2011.

OUTCOME MEASURES: Number of register-based psychiatric diagnoses. Additionally, symptoms of anxiety, depression, somatization, health anxiety, illness perception, and levels of educational attainment compared to age- and gender-matched individuals from the reference group.

RESULTS: We identified 723 Danish patients with a small, unrepaired ASD. Approximately 17% of the patients eligible for inclusion had one or more psychiatric diagnoses. The most common diagnoses were neurotic, stress-related, and somatoform disorders. A total of 140 patients (mean age 33 years) was included for examination of their mental health using psychiatric questionnaires and scales. Patients with small ASD had higher scores of depression and anxiety when compared to the reference group (0.57 ± 0.67 vs 0.39 ± 0.52; P < .001). Furthermore, patients reported more symptoms of somatization (0.51 ± 0.48 vs 0.34 ± 0.39; P < .001). Finally, a higher percentage of patients with an unrepaired ASD had no education beyond high school when compared to the reference group (33.3% vs 14.3%; P < .001) and a smaller proportion of patients had completed a short-cycle higher education (6.5% vs 16.1%; P = .002).

CONCLUSION: Patients with a small, unrepaired ASD in adult life have more symptoms of anxiety, depression, and somatization compared to the reference group. Furthermore, fewer patients had no education beyond high school. These results support the guidelines that adults with small ASD warrants regular lifelong follow-up in specialized clinics aware of not only adverse somatic outcome but also rates of depression and anxiety.

Original languageEnglish
JournalCongenital Heart Disease
ISSN1747-079X
DOIs
Publication statusE-pub ahead of print - 28 May 2019

Fingerprint

Atrial Heart Septal Defects
Mental Disorders
Anxiety
Depression
Psychiatry
Education
Somatoform Disorders
Educational Status
Checklist
Registries
Mental Health
Guidelines

Cite this

Udholm, Sebastian ; Nyboe, Camilla ; Dantoft, Thomas Meinertz ; Jørgensen, Torben ; Rask, Charlotte U ; Hjortdal, Vibeke E. / Small atrial septal defects are associated with psychiatric diagnoses, emotional distress, and lower educational levels. In: Congenital Heart Disease. 2019.
@article{8d340a674a514a7eb1ab8e7186ec7a37,
title = "Small atrial septal defects are associated with psychiatric diagnoses, emotional distress, and lower educational levels",
abstract = "OBJECTIVE: For the first time, we wish to assess the psychiatric burden in adult patients living with small, unrepaired atrial septal defects (ASD) using register-based data, combined with self-reported measures on levels emotional distress and educational status.DESIGN: A descriptive study using both the unique Danish registries and validated psychiatric questionnaires and scales, including: The Symptom Checklist, Whiteley-7, and Brief Illness Perception Questionnaire.PATIENTS: Adult patients with small, unrepaired ASD, diagnosed between 1953 and 2011.OUTCOME MEASURES: Number of register-based psychiatric diagnoses. Additionally, symptoms of anxiety, depression, somatization, health anxiety, illness perception, and levels of educational attainment compared to age- and gender-matched individuals from the reference group.RESULTS: We identified 723 Danish patients with a small, unrepaired ASD. Approximately 17{\%} of the patients eligible for inclusion had one or more psychiatric diagnoses. The most common diagnoses were neurotic, stress-related, and somatoform disorders. A total of 140 patients (mean age 33 years) was included for examination of their mental health using psychiatric questionnaires and scales. Patients with small ASD had higher scores of depression and anxiety when compared to the reference group (0.57 ± 0.67 vs 0.39 ± 0.52; P < .001). Furthermore, patients reported more symptoms of somatization (0.51 ± 0.48 vs 0.34 ± 0.39; P < .001). Finally, a higher percentage of patients with an unrepaired ASD had no education beyond high school when compared to the reference group (33.3{\%} vs 14.3{\%}; P < .001) and a smaller proportion of patients had completed a short-cycle higher education (6.5{\%} vs 16.1{\%}; P = .002).CONCLUSION: Patients with a small, unrepaired ASD in adult life have more symptoms of anxiety, depression, and somatization compared to the reference group. Furthermore, fewer patients had no education beyond high school. These results support the guidelines that adults with small ASD warrants regular lifelong follow-up in specialized clinics aware of not only adverse somatic outcome but also rates of depression and anxiety.",
author = "Sebastian Udholm and Camilla Nyboe and Dantoft, {Thomas Meinertz} and Torben J{\o}rgensen and Rask, {Charlotte U} and Hjortdal, {Vibeke E}",
note = "{\circledC} 2019 Wiley Periodicals, Inc.",
year = "2019",
month = "5",
day = "28",
doi = "10.1111/chd.12808",
language = "English",
journal = "Congenital Heart Disease",
issn = "1747-079X",
publisher = "Wiley-Blackwell",

}

Small atrial septal defects are associated with psychiatric diagnoses, emotional distress, and lower educational levels. / Udholm, Sebastian; Nyboe, Camilla; Dantoft, Thomas Meinertz; Jørgensen, Torben; Rask, Charlotte U; Hjortdal, Vibeke E.

In: Congenital Heart Disease, 28.05.2019.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Small atrial septal defects are associated with psychiatric diagnoses, emotional distress, and lower educational levels

AU - Udholm, Sebastian

AU - Nyboe, Camilla

AU - Dantoft, Thomas Meinertz

AU - Jørgensen, Torben

AU - Rask, Charlotte U

AU - Hjortdal, Vibeke E

N1 - © 2019 Wiley Periodicals, Inc.

PY - 2019/5/28

Y1 - 2019/5/28

N2 - OBJECTIVE: For the first time, we wish to assess the psychiatric burden in adult patients living with small, unrepaired atrial septal defects (ASD) using register-based data, combined with self-reported measures on levels emotional distress and educational status.DESIGN: A descriptive study using both the unique Danish registries and validated psychiatric questionnaires and scales, including: The Symptom Checklist, Whiteley-7, and Brief Illness Perception Questionnaire.PATIENTS: Adult patients with small, unrepaired ASD, diagnosed between 1953 and 2011.OUTCOME MEASURES: Number of register-based psychiatric diagnoses. Additionally, symptoms of anxiety, depression, somatization, health anxiety, illness perception, and levels of educational attainment compared to age- and gender-matched individuals from the reference group.RESULTS: We identified 723 Danish patients with a small, unrepaired ASD. Approximately 17% of the patients eligible for inclusion had one or more psychiatric diagnoses. The most common diagnoses were neurotic, stress-related, and somatoform disorders. A total of 140 patients (mean age 33 years) was included for examination of their mental health using psychiatric questionnaires and scales. Patients with small ASD had higher scores of depression and anxiety when compared to the reference group (0.57 ± 0.67 vs 0.39 ± 0.52; P < .001). Furthermore, patients reported more symptoms of somatization (0.51 ± 0.48 vs 0.34 ± 0.39; P < .001). Finally, a higher percentage of patients with an unrepaired ASD had no education beyond high school when compared to the reference group (33.3% vs 14.3%; P < .001) and a smaller proportion of patients had completed a short-cycle higher education (6.5% vs 16.1%; P = .002).CONCLUSION: Patients with a small, unrepaired ASD in adult life have more symptoms of anxiety, depression, and somatization compared to the reference group. Furthermore, fewer patients had no education beyond high school. These results support the guidelines that adults with small ASD warrants regular lifelong follow-up in specialized clinics aware of not only adverse somatic outcome but also rates of depression and anxiety.

AB - OBJECTIVE: For the first time, we wish to assess the psychiatric burden in adult patients living with small, unrepaired atrial septal defects (ASD) using register-based data, combined with self-reported measures on levels emotional distress and educational status.DESIGN: A descriptive study using both the unique Danish registries and validated psychiatric questionnaires and scales, including: The Symptom Checklist, Whiteley-7, and Brief Illness Perception Questionnaire.PATIENTS: Adult patients with small, unrepaired ASD, diagnosed between 1953 and 2011.OUTCOME MEASURES: Number of register-based psychiatric diagnoses. Additionally, symptoms of anxiety, depression, somatization, health anxiety, illness perception, and levels of educational attainment compared to age- and gender-matched individuals from the reference group.RESULTS: We identified 723 Danish patients with a small, unrepaired ASD. Approximately 17% of the patients eligible for inclusion had one or more psychiatric diagnoses. The most common diagnoses were neurotic, stress-related, and somatoform disorders. A total of 140 patients (mean age 33 years) was included for examination of their mental health using psychiatric questionnaires and scales. Patients with small ASD had higher scores of depression and anxiety when compared to the reference group (0.57 ± 0.67 vs 0.39 ± 0.52; P < .001). Furthermore, patients reported more symptoms of somatization (0.51 ± 0.48 vs 0.34 ± 0.39; P < .001). Finally, a higher percentage of patients with an unrepaired ASD had no education beyond high school when compared to the reference group (33.3% vs 14.3%; P < .001) and a smaller proportion of patients had completed a short-cycle higher education (6.5% vs 16.1%; P = .002).CONCLUSION: Patients with a small, unrepaired ASD in adult life have more symptoms of anxiety, depression, and somatization compared to the reference group. Furthermore, fewer patients had no education beyond high school. These results support the guidelines that adults with small ASD warrants regular lifelong follow-up in specialized clinics aware of not only adverse somatic outcome but also rates of depression and anxiety.

U2 - 10.1111/chd.12808

DO - 10.1111/chd.12808

M3 - Journal article

JO - Congenital Heart Disease

JF - Congenital Heart Disease

SN - 1747-079X

ER -