Abstract
Spironolactone is a synthetic aldosterone receptor antagonist, with a role off-label in various dermatological conditions. Its antiandrogenic properties make it suitable for diseases in which excess androgen production results in unwanted and psychologically distressing manifestations in susceptible females. Treatment with spironolactone aims to attenuate androgen-mediated conditions including acne, hidradenitis suppurativa, female pattern hair loss and hirsutism. We discuss the emerging utility of spironolactone in dermatology, its potential adverse effects and considerations for monitoring.
| Original language | English |
|---|---|
| Journal | Clinical and Experimental Dermatology |
| Volume | 45 |
| Issue number | 8 |
| Pages (from-to) | 986-993 |
| Number of pages | 8 |
| ISSN | 0307-6938 |
| DOIs | |
| Publication status | Published - 1 Dec 2020 |