Spironolactone in dermatology: uses in acne and beyond

T. N. Searle, F. Al-Niaimi, Faisal R. Ali

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)


Spironolactone is a synthetic aldosterone receptor antagonist, with a role off-label in various dermatological conditions. Its antiandrogenic properties make it suitable for diseases in which excess androgen production results in unwanted and psychologically distressing manifestations in susceptible females. Treatment with spironolactone aims to attenuate androgen-mediated conditions including acne, hidradenitis suppurativa, female pattern hair loss and hirsutism. We discuss the emerging utility of spironolactone in dermatology, its potential adverse effects and considerations for monitoring.

Original languageEnglish
JournalClinical and Experimental Dermatology
Issue number8
Pages (from-to)986-993
Number of pages8
Publication statusPublished - 1 Dec 2020


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