The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor

Mads Toft Søndergaard; Yingjie Liu; Kamilla Taunsig Larsen; Alma Nani; Xixi Tian; Christian Holt; Ruiwu Wang; Reinhard Wimmer; Filip Van Petegem; Michael Fill; S R Wayne Chen; Michael Toft Overgaard

doi:10.1074/jbc.M116.766253

The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor

Mads Toft Søndergaard, Yingjie Liu, Kamilla Taunsig Larsen, Alma Nani, Xixi Tian, Christian Holt, Ruiwu Wang, Reinhard Wimmer, Filip Van Petegem, Michael Fill, S R Wayne Chen, Michael Toft Overgaard

Research output: Contribution to journal › Journal article › Research › peer-review

18 Citations (Scopus)

Original language	English
Journal	Journal of Biological Chemistry
Volume	292
Pages (from-to)	1385-1395
Number of pages	11
ISSN	0021-9258
DOIs	https://doi.org/10.1074/jbc.M116.766253
Publication status	Published - Jan 2017

Access to Document

10.1074/jbc.M116.766253Licence: CC BY 4.0

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270481/pdf/zbc1385.pdfLicence: CC BY 4.0

Fingerprint Dive into the research topics of 'The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor'. Together they form a unique fingerprint.

Cite this

Søndergaard, M. T., Liu, Y., Larsen, K. T., Nani, A., Tian, X., Holt, C., Wang, R., Wimmer, R., Van Petegem, F., Fill, M., Chen, S. R. W., & Overgaard, M. T. (2017). The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. Journal of Biological Chemistry, 292, 1385-1395. https://doi.org/10.1074/jbc.M116.766253

Søndergaard, Mads Toft ; Liu, Yingjie ; Larsen, Kamilla Taunsig ; Nani, Alma ; Tian, Xixi ; Holt, Christian ; Wang, Ruiwu ; Wimmer, Reinhard ; Van Petegem, Filip ; Fill, Michael ; Chen, S R Wayne ; Overgaard, Michael Toft. / The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. In: Journal of Biological Chemistry. 2017 ; Vol. 292. pp. 1385-1395.

@article{80c26a3b5ebe4de9aa207b6eaa9ee5e5,

title = "The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor",

author = "S{\o}ndergaard, {Mads Toft} and Yingjie Liu and Larsen, {Kamilla Taunsig} and Alma Nani and Xixi Tian and Christian Holt and Ruiwu Wang and Reinhard Wimmer and {Van Petegem}, Filip and Michael Fill and Chen, {S R Wayne} and Overgaard, {Michael Toft}",

note = "Copyright {\textcopyright} 2016, The American Society for Biochemistry and Molecular Biology.",

year = "2017",

month = jan,

doi = "10.1074/jbc.M116.766253",

language = "English",

volume = "292",

pages = "1385--1395",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology, Inc.",

}

Søndergaard, MT, Liu, Y, Larsen, KT, Nani, A, Tian, X, Holt, C, Wang, R, Wimmer, R, Van Petegem, F, Fill, M, Chen, SRW & Overgaard, MT 2017, 'The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor', Journal of Biological Chemistry, vol. 292, pp. 1385-1395. https://doi.org/10.1074/jbc.M116.766253

The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. / Søndergaard, Mads Toft; Liu, Yingjie; Larsen, Kamilla Taunsig; Nani, Alma; Tian, Xixi; Holt, Christian; Wang, Ruiwu; Wimmer, Reinhard; Van Petegem, Filip; Fill, Michael; Chen, S R Wayne; Overgaard, Michael Toft.

In: Journal of Biological Chemistry, Vol. 292, 01.2017, p. 1385-1395.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor

AU - Søndergaard, Mads Toft

AU - Liu, Yingjie

AU - Larsen, Kamilla Taunsig

AU - Nani, Alma

AU - Tian, Xixi

AU - Holt, Christian

AU - Wang, Ruiwu

AU - Wimmer, Reinhard

AU - Van Petegem, Filip

AU - Fill, Michael

AU - Chen, S R Wayne

AU - Overgaard, Michael Toft

PY - 2017/1

Y1 - 2017/1

U2 - 10.1074/jbc.M116.766253

DO - 10.1074/jbc.M116.766253

M3 - Journal article

C2 - 27927985

VL - 292

SP - 1385

EP - 1395

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 0021-9258

ER -