The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor

Mads Toft Søndergaard, Yingjie Liu, Kamilla Taunsig Larsen, Alma Nani, Xixi Tian, Christian Holt, Ruiwu Wang, Reinhard Wimmer, Filip Van Petegem, Michael Fill, S R Wayne Chen, Michael Toft Overgaard

Research output: Contribution to journal › Journal article › Research › peer-review

13 Citations (Scopus)
Original languageEnglish
JournalJournal of Biological Chemistry
Volume292
Pages (from-to)1385-1395
Number of pages11
ISSN0021-9258
DOIs
Publication statusPublished - Jan 2017

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Ryanodine Receptor Calcium Release Channel
Calmodulin
Mutation

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Søndergaard, Mads Toft ; Liu, Yingjie ; Larsen, Kamilla Taunsig ; Nani, Alma ; Tian, Xixi ; Holt, Christian ; Wang, Ruiwu ; Wimmer, Reinhard ; Van Petegem, Filip ; Fill, Michael ; Chen, S R Wayne ; Overgaard, Michael Toft. / The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. In: Journal of Biological Chemistry. 2017 ; Vol. 292. pp. 1385-1395.
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author = "S{\o}ndergaard, {Mads Toft} and Yingjie Liu and Larsen, {Kamilla Taunsig} and Alma Nani and Xixi Tian and Christian Holt and Ruiwu Wang and Reinhard Wimmer and {Van Petegem}, Filip and Michael Fill and Chen, {S R Wayne} and Overgaard, {Michael Toft}",
note = "Copyright {\circledC} 2016, The American Society for Biochemistry and Molecular Biology.",
year = "2017",
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doi = "10.1074/jbc.M116.766253",
language = "English",
volume = "292",
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Søndergaard, MT, Liu, Y, Larsen, KT, Nani, A, Tian, X, Holt, C, Wang, R, Wimmer, R, Van Petegem, F, Fill, M, Chen, SRW & Overgaard, MT 2017, 'The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor', Journal of Biological Chemistry, vol. 292, pp. 1385-1395. https://doi.org/10.1074/jbc.M116.766253

The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. / Søndergaard, Mads Toft; Liu, Yingjie; Larsen, Kamilla Taunsig; Nani, Alma; Tian, Xixi; Holt, Christian; Wang, Ruiwu; Wimmer, Reinhard; Van Petegem, Filip; Fill, Michael; Chen, S R Wayne; Overgaard, Michael Toft.

In: Journal of Biological Chemistry, Vol. 292, 01.2017, p. 1385-1395.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor

AU - Søndergaard, Mads Toft

AU - Liu, Yingjie

AU - Larsen, Kamilla Taunsig

AU - Nani, Alma

AU - Tian, Xixi

AU - Holt, Christian

AU - Wang, Ruiwu

AU - Wimmer, Reinhard

AU - Van Petegem, Filip

AU - Fill, Michael

AU - Chen, S R Wayne

AU - Overgaard, Michael Toft

N1 - Copyright © 2016, The American Society for Biochemistry and Molecular Biology.

PY - 2017/1

Y1 - 2017/1

U2 - 10.1074/jbc.M116.766253

DO - 10.1074/jbc.M116.766253

M3 - Journal article

C2 - 27927985

VL - 292

SP - 1385

EP - 1395

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 0021-9258

ER -

Søndergaard MT, Liu Y, Larsen KT, Nani A, Tian X, Holt C et al. The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. Journal of Biological Chemistry. 2017 Jan;292:1385-1395. https://doi.org/10.1074/jbc.M116.766253

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