TY - JOUR
T1 - The effect of escalating heat stimulation on top of anesthetized skin
AU - Riccio, Daniele
AU - Lo Vecchio, Silvia
AU - Arendt-Nielsen, Lars
PY - 2023/1
Y1 - 2023/1
N2 - The relationship between itch and heat pain has been vastly explored. A 70-year-old study, showed the development of paradoxical itch following heat stimulation of anesthetized skin. The aim of this study was to re-evaluate, with more modern technologies and systematic approaches, this paradoxical itch effect. Escalating heat stimuli were applied to the local anesthetized skin of 19 healthy subjects, itch, and pain intensities were continuously assessed during the stimulation. As expected, pain sensation was significantly reduced by local intradermal anesthesia, however, no paradoxical itch sensations were observed for any of the stimulation temperatures.
AB - The relationship between itch and heat pain has been vastly explored. A 70-year-old study, showed the development of paradoxical itch following heat stimulation of anesthetized skin. The aim of this study was to re-evaluate, with more modern technologies and systematic approaches, this paradoxical itch effect. Escalating heat stimuli were applied to the local anesthetized skin of 19 healthy subjects, itch, and pain intensities were continuously assessed during the stimulation. As expected, pain sensation was significantly reduced by local intradermal anesthesia, however, no paradoxical itch sensations were observed for any of the stimulation temperatures.
U2 - 10.1097/itx.0000000000000065
DO - 10.1097/itx.0000000000000065
M3 - Journal article
SN - 2380-5048
VL - 8
JO - Itch
JF - Itch
IS - 1
M1 - e65
ER -