The effect of n-3 polyunsaturated fatty acids on leukotriene B(4) and leukotriene B(5) production from stimulated neutrophil granulocytes in patients with chronic kidney disease

T Maaløe; Erik Berg Schmidt; M Svensson; I V Aardestrup; J H Christensen

doi:10.1016/j.plefa.2011.04.004

The effect of n-3 polyunsaturated fatty acids on leukotriene B(4) and leukotriene B(5) production from stimulated neutrophil granulocytes in patients with chronic kidney disease

T Maaløe, Erik Berg Schmidt, M Svensson, I V Aardestrup, J H Christensen

Research output: Contribution to journal › Journal article › Research › peer-review

24 Citations (Scopus)

Abstract

The proinflammatory leukotriene B(4) (LTB(4)) may be of importance in the progression of chronic kidney disease (CKD). We investigated whether n-3 polyunsaturated fatty acids (PUFA) decrease LTB(4) and increase the formation of the less inflammatory leukotriene B(5) (LTB(5)) in patients with CKD. Fifty-six patients with CKD stage 2-5 were randomised to 2.4g n-3 PUFA or olive oil for 8 weeks. Compared to controls, n-3 PUFA significantly decreased release of LTB(4) (p

Original language	English
Journal	Prostaglandins, Leukotrienes & Essential Fatty Acids
Volume	85
Pages (from-to)	37-41
Number of pages	5
ISSN	0952-3278
DOIs	https://doi.org/10.1016/j.plefa.2011.04.004
Publication status	Published - 2011
Externally published	Yes

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Maaløe, T., Schmidt, E. B., Svensson, M., Aardestrup, I. V., & Christensen, J. H. (2011). The effect of n-3 polyunsaturated fatty acids on leukotriene B(4) and leukotriene B(5) production from stimulated neutrophil granulocytes in patients with chronic kidney disease. Prostaglandins, Leukotrienes & Essential Fatty Acids, 85, 37-41. https://doi.org/10.1016/j.plefa.2011.04.004

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title = "The effect of n-3 polyunsaturated fatty acids on leukotriene B(4) and leukotriene B(5) production from stimulated neutrophil granulocytes in patients with chronic kidney disease",

abstract = "The proinflammatory leukotriene B(4) (LTB(4)) may be of importance in the progression of chronic kidney disease (CKD). We investigated whether n-3 polyunsaturated fatty acids (PUFA) decrease LTB(4) and increase the formation of the less inflammatory leukotriene B(5) (LTB(5)) in patients with CKD. Fifty-six patients with CKD stage 2-5 were randomised to 2.4g n-3 PUFA or olive oil for 8 weeks. Compared to controls, n-3 PUFA significantly decreased release of LTB(4) (p",

author = "T Maal{\o}e and Schmidt, {Erik Berg} and M Svensson and Aardestrup, {I V} and Christensen, {J H}",

year = "2011",

doi = "10.1016/j.plefa.2011.04.004",

language = "English",

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pages = "37--41",

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Maaløe, T, Schmidt, EB, Svensson, M, Aardestrup, IV & Christensen, JH 2011, 'The effect of n-3 polyunsaturated fatty acids on leukotriene B(4) and leukotriene B(5) production from stimulated neutrophil granulocytes in patients with chronic kidney disease', Prostaglandins, Leukotrienes & Essential Fatty Acids, vol. 85, pp. 37-41. https://doi.org/10.1016/j.plefa.2011.04.004

The effect of n-3 polyunsaturated fatty acids on leukotriene B(4) and leukotriene B(5) production from stimulated neutrophil granulocytes in patients with chronic kidney disease. / Maaløe, T; Schmidt, Erik Berg; Svensson, M et al.
In: Prostaglandins, Leukotrienes & Essential Fatty Acids, Vol. 85, 2011, p. 37-41.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - The effect of n-3 polyunsaturated fatty acids on leukotriene B(4) and leukotriene B(5) production from stimulated neutrophil granulocytes in patients with chronic kidney disease

AU - Maaløe, T

AU - Schmidt, Erik Berg

AU - Svensson, M

AU - Aardestrup, I V

AU - Christensen, J H

PY - 2011

Y1 - 2011

N2 - The proinflammatory leukotriene B(4) (LTB(4)) may be of importance in the progression of chronic kidney disease (CKD). We investigated whether n-3 polyunsaturated fatty acids (PUFA) decrease LTB(4) and increase the formation of the less inflammatory leukotriene B(5) (LTB(5)) in patients with CKD. Fifty-six patients with CKD stage 2-5 were randomised to 2.4g n-3 PUFA or olive oil for 8 weeks. Compared to controls, n-3 PUFA significantly decreased release of LTB(4) (p

AB - The proinflammatory leukotriene B(4) (LTB(4)) may be of importance in the progression of chronic kidney disease (CKD). We investigated whether n-3 polyunsaturated fatty acids (PUFA) decrease LTB(4) and increase the formation of the less inflammatory leukotriene B(5) (LTB(5)) in patients with CKD. Fifty-six patients with CKD stage 2-5 were randomised to 2.4g n-3 PUFA or olive oil for 8 weeks. Compared to controls, n-3 PUFA significantly decreased release of LTB(4) (p

U2 - 10.1016/j.plefa.2011.04.004

DO - 10.1016/j.plefa.2011.04.004

M3 - Journal article

SN - 0952-3278

VL - 85

SP - 37

EP - 41

JO - Prostaglandins, Leukotrienes & Essential Fatty Acids

JF - Prostaglandins, Leukotrienes & Essential Fatty Acids

ER -

The effect of n-3 polyunsaturated fatty acids on leukotriene B(4) and leukotriene B(5) production from stimulated neutrophil granulocytes in patients with chronic kidney disease

Abstract

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