The mechanical and hemodynamic effects of left ventricular pacing in heart failure with preserved ejection fraction and left bundle branch block

Daniel J. Friedman; Kasper Emerek; Peter Søgaard; Maryam Vejdani-Jahromi; Joseph Kisslo; Brett D. Atwater

doi:10.1016/j.jelectrocard.2018.07.004

The mechanical and hemodynamic effects of left ventricular pacing in heart failure with preserved ejection fraction and left bundle branch block

Daniel J. Friedman, Kasper Emerek, Peter Søgaard, Maryam Vejdani-Jahromi, Joseph Kisslo, Brett D. Atwater

Research output: Contribution to journal › Journal article › Research › peer-review

5 Citations (Scopus)

Abstract

Cardiac resynchronization therapy (CRT) has revolutionized the care of patients with heart failure with reduced ejection fraction (HFrEF) and left bundle branch block (LBBB); some hypothesize that electrical resynchronization may also benefit patients with heart failure with preserved ejection fraction (HFpEF) and LBBB. We assessed the acute hemodynamic and mechanical impact of temporary LV pacing in 2 patients with HFpEF and LBBB and a “classic” pattern of echocardiographic dyssynchrony. LV pacing facilitated electrical resynchronization with acute resolution of mechanical dyssynchrony and improvements in invasively and non-invasively measured global cardiac function, due in part to shortening of the isovolumetric contraction period.

Original language	English
Journal	Journal of Electrocardiology
Volume	51
Issue number	5
Pages (from-to)	859-862
Number of pages	4
ISSN	0022-0736
DOIs	https://doi.org/10.1016/j.jelectrocard.2018.07.004
Publication status	Published - 1 Sept 2018

Keywords

Cardiac resynchronization therapy
Heart failure with preserved ejection fraction
Left bundle branch block

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10.1016/j.jelectrocard.2018.07.004

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777548/

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The mechanical and hemodynamic effects of left ventricular pacing in heart failure with preserved ejection fraction and left bundle branch block. / Friedman, Daniel J.; Emerek, Kasper ; Søgaard, Peter et al.
In: Journal of Electrocardiology, Vol. 51, No. 5, 01.09.2018, p. 859-862.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - The mechanical and hemodynamic effects of left ventricular pacing in heart failure with preserved ejection fraction and left bundle branch block

AU - Friedman, Daniel J.

AU - Emerek, Kasper

AU - Søgaard, Peter

AU - Vejdani-Jahromi, Maryam

AU - Kisslo, Joseph

AU - Atwater, Brett D.

PY - 2018/9/1

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N2 - Cardiac resynchronization therapy (CRT) has revolutionized the care of patients with heart failure with reduced ejection fraction (HFrEF) and left bundle branch block (LBBB); some hypothesize that electrical resynchronization may also benefit patients with heart failure with preserved ejection fraction (HFpEF) and LBBB. We assessed the acute hemodynamic and mechanical impact of temporary LV pacing in 2 patients with HFpEF and LBBB and a “classic” pattern of echocardiographic dyssynchrony. LV pacing facilitated electrical resynchronization with acute resolution of mechanical dyssynchrony and improvements in invasively and non-invasively measured global cardiac function, due in part to shortening of the isovolumetric contraction period.

AB - Cardiac resynchronization therapy (CRT) has revolutionized the care of patients with heart failure with reduced ejection fraction (HFrEF) and left bundle branch block (LBBB); some hypothesize that electrical resynchronization may also benefit patients with heart failure with preserved ejection fraction (HFpEF) and LBBB. We assessed the acute hemodynamic and mechanical impact of temporary LV pacing in 2 patients with HFpEF and LBBB and a “classic” pattern of echocardiographic dyssynchrony. LV pacing facilitated electrical resynchronization with acute resolution of mechanical dyssynchrony and improvements in invasively and non-invasively measured global cardiac function, due in part to shortening of the isovolumetric contraction period.

KW - Cardiac resynchronization therapy

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DO - 10.1016/j.jelectrocard.2018.07.004

M3 - Journal article

SN - 0022-0736

VL - 51

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JO - Journal of Electrocardiology

JF - Journal of Electrocardiology

IS - 5

ER -

The mechanical and hemodynamic effects of left ventricular pacing in heart failure with preserved ejection fraction and left bundle branch block

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Keywords

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