The North Jutland County Diabetic Retinopathy Study (NCDRS). Population characteristics.

L.L. Knudsen, H.H. Lervang, Søren Lundbye-Christensen, Anders Gorst-Rasmussen

Research output: Contribution to conference without publisher/journalPosterResearch

Abstract

Abstract Purpose: Several population based studies have reported blood glucose levels and blood pressure to be risk factors for the development of proliferativ retinopathy and diabetic maculopathy. Despite their importance, these studies were initiated more than two decades ago and may therefore reflect the treatment and population composition of a previous era. Studies of the present diabetic population are therefore in demand. Methods: The present cross–section study included 656 type 1 and 328 type 2 diabetic subjects undergoing diabetic retinopathy screening. Crude prevalence rates for proliferative diabetic retinopathy, maculopathy, several specific lesions and non–ophthalmic findings were assessed together with their association to a simplified and internationally approved retinal grading. Results: The crude prevalence of proliferative retinopathy was found to be 5.6 % and 0.9 % for type 1 and type 2 diabetes. Equivalent prevalence rates for diabetic maculopathy were 7.9 % and 12.8 %, respectively. The most frequently occuring retinal manifestations (microaneurysms, bleedings, hard exudates and soft exudates) were found to increase in number up to retinopathy level 3 followed by decrease. The prevalence of diabetic maculopathy also increased up to retinopathy level 3 followed by decrease. Less frequently occuring retinal manifestations occured at frequences in the range of 0.0–2.5 % and were only observed at retinopathy level 3 and 4. Conclusions: The prevalence of proliferative retinopathy is lower than that of previous studies, possibly due to improved blood glucose regulation, while the prevalence of diabetic maculopathy is similar or possibly slightly higher. This could suggest that other and more important risk factors than blood glucose levels dominate the development and progression of diabetic maculopathy.
Original languageEnglish
Publication date2006
Number of pages1
Publication statusPublished - 2006
EventARVO 2006 Annual Meeting - Ft. Lauderdale, Florida, United States
Duration: 30 Apr 20064 May 2006

Conference

ConferenceARVO 2006 Annual Meeting
CountryUnited States
CityFt. Lauderdale, Florida
Period30/04/200604/05/2006

Fingerprint

Diabetic Retinopathy
Population Characteristics
Blood Glucose
Exudates and Transudates
Population
Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus
Hemorrhage
Blood Pressure

Cite this

Knudsen, L. L., Lervang, H. H., Lundbye-Christensen, S., & Gorst-Rasmussen, A. (2006). The North Jutland County Diabetic Retinopathy Study (NCDRS). Population characteristics.. Poster session presented at ARVO 2006 Annual Meeting, Ft. Lauderdale, Florida, United States.
Knudsen, L.L. ; Lervang, H.H. ; Lundbye-Christensen, Søren ; Gorst-Rasmussen, Anders. / The North Jutland County Diabetic Retinopathy Study (NCDRS). Population characteristics. Poster session presented at ARVO 2006 Annual Meeting, Ft. Lauderdale, Florida, United States.1 p.
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title = "The North Jutland County Diabetic Retinopathy Study (NCDRS). Population characteristics.",
abstract = "Abstract Purpose: Several population based studies have reported blood glucose levels and blood pressure to be risk factors for the development of proliferativ retinopathy and diabetic maculopathy. Despite their importance, these studies were initiated more than two decades ago and may therefore reflect the treatment and population composition of a previous era. Studies of the present diabetic population are therefore in demand. Methods: The present cross–section study included 656 type 1 and 328 type 2 diabetic subjects undergoing diabetic retinopathy screening. Crude prevalence rates for proliferative diabetic retinopathy, maculopathy, several specific lesions and non–ophthalmic findings were assessed together with their association to a simplified and internationally approved retinal grading. Results: The crude prevalence of proliferative retinopathy was found to be 5.6 {\%} and 0.9 {\%} for type 1 and type 2 diabetes. Equivalent prevalence rates for diabetic maculopathy were 7.9 {\%} and 12.8 {\%}, respectively. The most frequently occuring retinal manifestations (microaneurysms, bleedings, hard exudates and soft exudates) were found to increase in number up to retinopathy level 3 followed by decrease. The prevalence of diabetic maculopathy also increased up to retinopathy level 3 followed by decrease. Less frequently occuring retinal manifestations occured at frequences in the range of 0.0–2.5 {\%} and were only observed at retinopathy level 3 and 4. Conclusions: The prevalence of proliferative retinopathy is lower than that of previous studies, possibly due to improved blood glucose regulation, while the prevalence of diabetic maculopathy is similar or possibly slightly higher. This could suggest that other and more important risk factors than blood glucose levels dominate the development and progression of diabetic maculopathy.",
author = "L.L. Knudsen and H.H. Lervang and S{\o}ren Lundbye-Christensen and Anders Gorst-Rasmussen",
note = "Serie: Investigative Ophthalmology and Visual Science, Association for Research in Vision and Ophthalmology (ARVO), E-abst:331, 47, 0146-0404, 1552-5783; null ; Conference date: 30-04-2006 Through 04-05-2006",
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Knudsen, LL, Lervang, HH, Lundbye-Christensen, S & Gorst-Rasmussen, A 2006, 'The North Jutland County Diabetic Retinopathy Study (NCDRS). Population characteristics.', Ft. Lauderdale, Florida, United States, 30/04/2006 - 04/05/2006, .

The North Jutland County Diabetic Retinopathy Study (NCDRS). Population characteristics. / Knudsen, L.L.; Lervang, H.H.; Lundbye-Christensen, Søren; Gorst-Rasmussen, Anders.

2006. Poster session presented at ARVO 2006 Annual Meeting, Ft. Lauderdale, Florida, United States.

Research output: Contribution to conference without publisher/journalPosterResearch

TY - CONF

T1 - The North Jutland County Diabetic Retinopathy Study (NCDRS). Population characteristics.

AU - Knudsen, L.L.

AU - Lervang, H.H.

AU - Lundbye-Christensen, Søren

AU - Gorst-Rasmussen, Anders

N1 - Serie: Investigative Ophthalmology and Visual Science, Association for Research in Vision and Ophthalmology (ARVO), E-abst:331, 47, 0146-0404, 1552-5783

PY - 2006

Y1 - 2006

N2 - Abstract Purpose: Several population based studies have reported blood glucose levels and blood pressure to be risk factors for the development of proliferativ retinopathy and diabetic maculopathy. Despite their importance, these studies were initiated more than two decades ago and may therefore reflect the treatment and population composition of a previous era. Studies of the present diabetic population are therefore in demand. Methods: The present cross–section study included 656 type 1 and 328 type 2 diabetic subjects undergoing diabetic retinopathy screening. Crude prevalence rates for proliferative diabetic retinopathy, maculopathy, several specific lesions and non–ophthalmic findings were assessed together with their association to a simplified and internationally approved retinal grading. Results: The crude prevalence of proliferative retinopathy was found to be 5.6 % and 0.9 % for type 1 and type 2 diabetes. Equivalent prevalence rates for diabetic maculopathy were 7.9 % and 12.8 %, respectively. The most frequently occuring retinal manifestations (microaneurysms, bleedings, hard exudates and soft exudates) were found to increase in number up to retinopathy level 3 followed by decrease. The prevalence of diabetic maculopathy also increased up to retinopathy level 3 followed by decrease. Less frequently occuring retinal manifestations occured at frequences in the range of 0.0–2.5 % and were only observed at retinopathy level 3 and 4. Conclusions: The prevalence of proliferative retinopathy is lower than that of previous studies, possibly due to improved blood glucose regulation, while the prevalence of diabetic maculopathy is similar or possibly slightly higher. This could suggest that other and more important risk factors than blood glucose levels dominate the development and progression of diabetic maculopathy.

AB - Abstract Purpose: Several population based studies have reported blood glucose levels and blood pressure to be risk factors for the development of proliferativ retinopathy and diabetic maculopathy. Despite their importance, these studies were initiated more than two decades ago and may therefore reflect the treatment and population composition of a previous era. Studies of the present diabetic population are therefore in demand. Methods: The present cross–section study included 656 type 1 and 328 type 2 diabetic subjects undergoing diabetic retinopathy screening. Crude prevalence rates for proliferative diabetic retinopathy, maculopathy, several specific lesions and non–ophthalmic findings were assessed together with their association to a simplified and internationally approved retinal grading. Results: The crude prevalence of proliferative retinopathy was found to be 5.6 % and 0.9 % for type 1 and type 2 diabetes. Equivalent prevalence rates for diabetic maculopathy were 7.9 % and 12.8 %, respectively. The most frequently occuring retinal manifestations (microaneurysms, bleedings, hard exudates and soft exudates) were found to increase in number up to retinopathy level 3 followed by decrease. The prevalence of diabetic maculopathy also increased up to retinopathy level 3 followed by decrease. Less frequently occuring retinal manifestations occured at frequences in the range of 0.0–2.5 % and were only observed at retinopathy level 3 and 4. Conclusions: The prevalence of proliferative retinopathy is lower than that of previous studies, possibly due to improved blood glucose regulation, while the prevalence of diabetic maculopathy is similar or possibly slightly higher. This could suggest that other and more important risk factors than blood glucose levels dominate the development and progression of diabetic maculopathy.

M3 - Poster

ER -

Knudsen LL, Lervang HH, Lundbye-Christensen S, Gorst-Rasmussen A. The North Jutland County Diabetic Retinopathy Study (NCDRS). Population characteristics.. 2006. Poster session presented at ARVO 2006 Annual Meeting, Ft. Lauderdale, Florida, United States.