TY - JOUR
T1 - The role of bystanders, first responders, and emergency medical service providers in timely defibrillation and related outcomes after out-of-hospital cardiac arrest
T2 - Results from a statewide registry
AU - Hansen, Carolina Malta
AU - Sørensen, Kristian Dahl Kragholm
AU - Granger, Christopher B
AU - Pearson, David A
AU - Tyson, Clark
AU - Monk, Lisa
AU - Corbett, Claire
AU - Nelson, R Darrell
AU - Dupre, Matthew E
AU - Fosbøl, Emil L
AU - Strauss, Benjamin
AU - Fordyce, Christopher B
AU - McNally, Bryan
AU - Jollis, James G
N1 - Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
PY - 2015
Y1 - 2015
N2 - AIM: Defibrillation by bystanders and first responders has been associated with increased survival, but limited data are available from non-metropolitan areas. We examined time from 911-call to defibrillation (according to who defibrillated patients) and survival in North Carolina.METHODS: Through the Cardiac Arrest Registry to Enhance Survival, we identified 1732 defibrillated out-of-hospital cardiac arrests from counties with complete case capture (population 2.7 million) from 2010 to 2013.RESULTS: Most patients (60.9%) were defibrillated in >10min. A minority (8.0%) was defibrillated <5min; most of these patients were defibrillated by first responders (51.8%) and bystanders (33.1%), independent of location of arrest (residential or public). Bystanders initiated cardiopulmonary resuscitation (CPR) in 49.0% of cases and defibrillated 13.4% of those. Survival decreased with increasing time to defibrillation (<2min: 59.1%; 2 to <5min: 38.5%; 5-10min: 33.1%; >10min: 13.2%). Odds of survival with favorable neurologic outcome adjusted for age, sex, and bystander CPR improved with faster defibrillation (<2min: OR 7.73 [95% CI 3.19-18.73]; 2 to <5min: 3.78 [2.45-5.84]; 5-10min: 3.16 [2.42-4.12]; >10min: reference).CONCLUSION: Bystanders and first responders were mainly responsible for defibrillation within 5min, independent of location of arrest. Bystanders initiated CPR in half of the cardiac arrest cases but only defibrillated a minority of those. Timely defibrillation and defibrillation by bystanders and/or first responders were strongly associated with increased survival. Strategic efforts to increase bystander and first-responder defibrillation are warranted to increase survival after out-of-hospital cardiac arrest.
AB - AIM: Defibrillation by bystanders and first responders has been associated with increased survival, but limited data are available from non-metropolitan areas. We examined time from 911-call to defibrillation (according to who defibrillated patients) and survival in North Carolina.METHODS: Through the Cardiac Arrest Registry to Enhance Survival, we identified 1732 defibrillated out-of-hospital cardiac arrests from counties with complete case capture (population 2.7 million) from 2010 to 2013.RESULTS: Most patients (60.9%) were defibrillated in >10min. A minority (8.0%) was defibrillated <5min; most of these patients were defibrillated by first responders (51.8%) and bystanders (33.1%), independent of location of arrest (residential or public). Bystanders initiated cardiopulmonary resuscitation (CPR) in 49.0% of cases and defibrillated 13.4% of those. Survival decreased with increasing time to defibrillation (<2min: 59.1%; 2 to <5min: 38.5%; 5-10min: 33.1%; >10min: 13.2%). Odds of survival with favorable neurologic outcome adjusted for age, sex, and bystander CPR improved with faster defibrillation (<2min: OR 7.73 [95% CI 3.19-18.73]; 2 to <5min: 3.78 [2.45-5.84]; 5-10min: 3.16 [2.42-4.12]; >10min: reference).CONCLUSION: Bystanders and first responders were mainly responsible for defibrillation within 5min, independent of location of arrest. Bystanders initiated CPR in half of the cardiac arrest cases but only defibrillated a minority of those. Timely defibrillation and defibrillation by bystanders and/or first responders were strongly associated with increased survival. Strategic efforts to increase bystander and first-responder defibrillation are warranted to increase survival after out-of-hospital cardiac arrest.
U2 - 10.1016/j.resuscitation.2015.09.002
DO - 10.1016/j.resuscitation.2015.09.002
M3 - Journal article
C2 - 26386371
SN - 0300-9572
VL - 96
SP - 303
EP - 309
JO - Resuscitation
JF - Resuscitation
ER -