Understanding the sensory irregularities of esophageal disease

Adam D Farmer, Christina Brock, Jens Brøndum Frøkjaer, Hans Gregersen, Sheeba Khan, Dina Lelic, Christian Lottrup, Asbjørn Mohr Drewes

Research output: Contribution to journalReview articlepeer-review

6 Citations (Scopus)

Abstract

Symptoms relating to esophageal sensory abnormalities can be encountered in the clinical environment. Such sensory abnormalities may be present in demonstrable disease, such as erosive esophagitis, and in the ostensibly normal esophagus, such as non-erosive reflux disease or functional chest pain. In this review, the authors discuss esophageal sensation and the esophageal pain system. In addition, the authors provide a primer concerning the techniques that are available for investigating the autonomic nervous system, neuroimaging and neurophysiology of esophageal sensory function. Such technological advances, whilst not readily available in the clinic may facilitate the stratification and individualization of therapy in disorders of esophageal sensation in the future.

Original languageEnglish
JournalExpert Review of Gastroenterology & Hepatology
Volume10
Issue number8
Pages (from-to)907-914
Number of pages8
ISSN1747-4124
DOIs
Publication statusPublished - 18 Feb 2016

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