Validation of the Endoscopic Part of the Spigelman Classification for Evaluating Duodenal Adenomatosis in Familial Adenomatous Polyposis: A Prospective Study of Interrater and Intrarater Reliability

John Gásdal Karstensen*, Steffen Bülow, Johan Burisch, Mark Bremholm Ellebæk, Marcin Ostapiuk, Hans Christian Pommergaard, Palle Nordblad Schmidt

*Corresponding author for this work

Research output: Contribution to journalLetterpeer-review

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Abstract

INTRODUCTION: In patients with familial adenomatous polyposis, the Spigelman classification is recommended for staging and risk stratification of duodenal adenomatosis. Although the classification has been used for decades, it has never been formally validated.

METHODS: We included consecutive FAP patients undergoing upper gastrointestinal endoscopic surveillance and evaluated the inter- and intrarater reliability of the Spigelman classification.

RESULTS: The interrater reliability of the endoscopic parameters and the Spigelman classification was good and excellent, respectively. The intrarater reliability of the endoscopic parameters and the Spigelman classification was moderate and good, respectively.

DISCUSSION: The results support continued use of the Spigelman classification as the primary end point for future studies and as key endoscopic performance measure.

Original languageEnglish
JournalThe American Journal of Gastroenterology
Volume117
Issue number2
Pages (from-to)343-345
Number of pages3
ISSN0002-9270
DOIs
Publication statusPublished - Feb 2022

Bibliographical note

Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.

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