TY - JOUR
T1 - VEXAS-genvarianter forklarer tidligere uerkendt klinisk syndrom
AU - Rasch, Mads Nyhuus Bendix
AU - Szabados, Fruzsina
AU - Jensen, Jens Magnus Bernth
AU - Nielsen, Kirstine Overgaard
AU - Hauge, Ellen-Margrethe
AU - Troldborg, Anne
PY - 2022/10/3
Y1 - 2022/10/3
N2 - This review aims to make clinicians aware of the newly described syndrome, VEXAS. VEXAS should become an obvious differential diagnosis in cases of unexplained inflammation, anemia, and rheumatological and/or hematological manifestations. Patients with VEXAS are typically male aged > 60, with inflammation, and macrocytic anaemia. On suspicion of cancer or infections patients have frequently been exposed to extensive diagnostic procedures and hospital admissions. In this review, we summarise the current knowledge of VEXAS regarding pathogenesis, symptoms, diagnosis, and treatment.
AB - This review aims to make clinicians aware of the newly described syndrome, VEXAS. VEXAS should become an obvious differential diagnosis in cases of unexplained inflammation, anemia, and rheumatological and/or hematological manifestations. Patients with VEXAS are typically male aged > 60, with inflammation, and macrocytic anaemia. On suspicion of cancer or infections patients have frequently been exposed to extensive diagnostic procedures and hospital admissions. In this review, we summarise the current knowledge of VEXAS regarding pathogenesis, symptoms, diagnosis, and treatment.
KW - Anemia/etiology
KW - Anemia, Macrocytic/etiology
KW - Diagnosis, Differential
KW - Humans
KW - Inflammation/complications
KW - Male
KW - Syndrome
M3 - Tidsskriftartikel
C2 - 36205150
SN - 0041-5782
VL - 184
JO - Ugeskrift for Læger
JF - Ugeskrift for Læger
M1 - V03220225
ER -