Plasma YKL-40 and all-cause mortality in patients with chronic obstructive pulmonary disease

Dennis Back Holmgaard; Lone H Mygind; Ingrid L Titlestad; Hanne Madsen; Svend Stenvang Pedersen; Julia Sidenius Johansen; Court Pedersen

doi:10.1186/1471-2466-13-77

Plasma YKL-40 and all-cause mortality in patients with chronic obstructive pulmonary disease

Dennis Back Holmgaard, Lone H Mygind, Ingrid L Titlestad, Hanne Madsen, Svend Stenvang Pedersen, Julia Sidenius Johansen, Court Pedersen

Research output: Contribution to journal › Journal article › Research › peer-review

23 Citations (Scopus)

Abstract

Chronic obstructive pulmonary disease (COPD) is hallmarked by inflammatory processes and a progressive decline of lung function. YKL-40 is a potential biomarker of inflammation and mortality in patients suffering from inflammatory lung disease, but its prognostic value in patients with COPD remains unknown. We investigated whether high plasma YKL-40 was associated with increased mortality in patients with moderate to very severe COPD.

Original language	English
Journal	B M C Pulmonary Medicine
Volume	13
Issue number	1
Pages (from-to)	77
ISSN	1471-2466
DOIs	https://doi.org/10.1186/1471-2466-13-77
Publication status	Published - 2013

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title = "Plasma YKL-40 and all-cause mortality in patients with chronic obstructive pulmonary disease",

abstract = "Chronic obstructive pulmonary disease (COPD) is hallmarked by inflammatory processes and a progressive decline of lung function. YKL-40 is a potential biomarker of inflammation and mortality in patients suffering from inflammatory lung disease, but its prognostic value in patients with COPD remains unknown. We investigated whether high plasma YKL-40 was associated with increased mortality in patients with moderate to very severe COPD.",

author = "Holmgaard, {Dennis Back} and Mygind, {Lone H} and Titlestad, {Ingrid L} and Hanne Madsen and Pedersen, {Svend Stenvang} and Johansen, {Julia Sidenius} and Court Pedersen",

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AU - Holmgaard, Dennis Back

AU - Mygind, Lone H

AU - Titlestad, Ingrid L

AU - Madsen, Hanne

AU - Pedersen, Svend Stenvang

AU - Johansen, Julia Sidenius

AU - Pedersen, Court

PY - 2013

Y1 - 2013

N2 - Chronic obstructive pulmonary disease (COPD) is hallmarked by inflammatory processes and a progressive decline of lung function. YKL-40 is a potential biomarker of inflammation and mortality in patients suffering from inflammatory lung disease, but its prognostic value in patients with COPD remains unknown. We investigated whether high plasma YKL-40 was associated with increased mortality in patients with moderate to very severe COPD.

AB - Chronic obstructive pulmonary disease (COPD) is hallmarked by inflammatory processes and a progressive decline of lung function. YKL-40 is a potential biomarker of inflammation and mortality in patients suffering from inflammatory lung disease, but its prognostic value in patients with COPD remains unknown. We investigated whether high plasma YKL-40 was associated with increased mortality in patients with moderate to very severe COPD.

U2 - 10.1186/1471-2466-13-77

DO - 10.1186/1471-2466-13-77

M3 - Journal article

C2 - 24373580

SN - 1471-2466

VL - 13

SP - 77

JO - B M C Pulmonary Medicine

JF - B M C Pulmonary Medicine

IS - 1

ER -

Plasma YKL-40 and all-cause mortality in patients with chronic obstructive pulmonary disease

Abstract

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