Effect of single-dose imipramine on chronic low-back and experimental pain

A randomized controlled trial

Jürg Schliessbach*, Andreas Siegenthaler, Lukas Bütikofer, Andreas Limacher, Peter Juni, Pascal H. Vuilleumier, Ulrike Stamer, Lars Arendt-Nielsen, Michele Curatolo

*Corresponding author

Research output: Contribution to journalJournal articleResearchpeer-review

306 Downloads (Pure)
Original languageEnglish
Article numbere0195776
JournalPLOS ONE
Volume13
Issue number5
Pages (from-to)e0195776
Number of pages15
ISSN1932-6203
DOIs
Publication statusPublished - 1 May 2018

Fingerprint

Imipramine
Low Back Pain
Cytochrome P-450 CYP2D6
pain
Randomized Controlled Trials
Pain Threshold
Analgesics
dosage
Tricyclic Antidepressive Agents
cytochrome P-450
Placebos
antidepressants
analgesic effect
Genotype
Pressure
Musculoskeletal Pain
placebos
Pharmacogenetics
Neuralgia
Metabolism

Keywords

  • Adult
  • Chronic Pain/drug therapy
  • Cytochrome P-450 CYP2D6/genetics
  • Female
  • Genotype
  • Humans
  • Imipramine/adverse effects
  • Low Back Pain/drug therapy
  • Male
  • Pain Measurement

Cite this

Schliessbach, J., Siegenthaler, A., Bütikofer, L., Limacher, A., Juni, P., Vuilleumier, P. H., ... Curatolo, M. (2018). Effect of single-dose imipramine on chronic low-back and experimental pain: A randomized controlled trial. PLOS ONE, 13(5), e0195776. [e0195776]. https://doi.org/10.1371/journal.pone.0195776
Schliessbach, Jürg ; Siegenthaler, Andreas ; Bütikofer, Lukas ; Limacher, Andreas ; Juni, Peter ; Vuilleumier, Pascal H. ; Stamer, Ulrike ; Arendt-Nielsen, Lars ; Curatolo, Michele. / Effect of single-dose imipramine on chronic low-back and experimental pain : A randomized controlled trial. In: PLOS ONE. 2018 ; Vol. 13, No. 5. pp. e0195776.
@article{20490388479c48e987a8ee8b7a1651fb,
title = "Effect of single-dose imipramine on chronic low-back and experimental pain: A randomized controlled trial",
keywords = "Adult, Chronic Pain/drug therapy, Cytochrome P-450 CYP2D6/genetics, Female, Genotype, Humans, Imipramine/adverse effects, Low Back Pain/drug therapy, Male, Pain Measurement",
author = "J{\"u}rg Schliessbach and Andreas Siegenthaler and Lukas B{\"u}tikofer and Andreas Limacher and Peter Juni and Vuilleumier, {Pascal H.} and Ulrike Stamer and Lars Arendt-Nielsen and Michele Curatolo",
year = "2018",
month = "5",
day = "1",
doi = "10.1371/journal.pone.0195776",
language = "English",
volume = "13",
pages = "e0195776",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "5",

}

Schliessbach, J, Siegenthaler, A, Bütikofer, L, Limacher, A, Juni, P, Vuilleumier, PH, Stamer, U, Arendt-Nielsen, L & Curatolo, M 2018, 'Effect of single-dose imipramine on chronic low-back and experimental pain: A randomized controlled trial', PLOS ONE, vol. 13, no. 5, e0195776, pp. e0195776. https://doi.org/10.1371/journal.pone.0195776

Effect of single-dose imipramine on chronic low-back and experimental pain : A randomized controlled trial. / Schliessbach, Jürg; Siegenthaler, Andreas; Bütikofer, Lukas; Limacher, Andreas; Juni, Peter; Vuilleumier, Pascal H.; Stamer, Ulrike; Arendt-Nielsen, Lars; Curatolo, Michele.

In: PLOS ONE, Vol. 13, No. 5, e0195776, 01.05.2018, p. e0195776.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Effect of single-dose imipramine on chronic low-back and experimental pain

T2 - A randomized controlled trial

AU - Schliessbach, Jürg

AU - Siegenthaler, Andreas

AU - Bütikofer, Lukas

AU - Limacher, Andreas

AU - Juni, Peter

AU - Vuilleumier, Pascal H.

AU - Stamer, Ulrike

AU - Arendt-Nielsen, Lars

AU - Curatolo, Michele

PY - 2018/5/1

Y1 - 2018/5/1

KW - Adult

KW - Chronic Pain/drug therapy

KW - Cytochrome P-450 CYP2D6/genetics

KW - Female

KW - Genotype

KW - Humans

KW - Imipramine/adverse effects

KW - Low Back Pain/drug therapy

KW - Male

KW - Pain Measurement

U2 - 10.1371/journal.pone.0195776

DO - 10.1371/journal.pone.0195776

M3 - Journal article

VL - 13

SP - e0195776

JO - P L o S One

JF - P L o S One

SN - 1932-6203

IS - 5

M1 - e0195776

ER -

Schliessbach J, Siegenthaler A, Bütikofer L, Limacher A, Juni P, Vuilleumier PH et al. Effect of single-dose imipramine on chronic low-back and experimental pain: A randomized controlled trial. PLOS ONE. 2018 May 1;13(5):e0195776. e0195776. https://doi.org/10.1371/journal.pone.0195776