ESPEN practical guideline on clinical nutrition in acute and chronic pancreatitis

Marianna Arvanitakis*, Johann Ockenga, Mihailo Bezmarevic, Luca Gianotti, Željko Krznarić, Dileep N. Lobo, Christian Löser, Christian Madl, Remy Meier, Mary Phillips, Henrik Højgaard Rasmussen, Jeanin E. Van Hooft, Stephan C. Bischoff

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Both acute and chronic pancreatitis are frequent diseases of the pancreas, which, despite being of benign nature, are related to a significant risk of malnutrition and may require nutritional support. Acute necrotizing pancreatitis is encountered in 20 % of patients with acute pancreatitis, is associated with increased morbidity and mortality, and may require artificial nutrition by enteral or parenteral route, as well as additional endoscopic, radiological or surgical interventions. Chronic pancreatitis represents a chronic inflammation of the pancreatic gland with development of fibrosis. Abdominal pain leading to decreased oral intake, as well as exocrine and endocrine failure are frequent complications of the disease. All of the above represent risk factors related to malnutrition. Therefore, patients with chronic pancreatitis should be considered at risk, screened and supplemented accordingly. Moreover, osteoporosis and increased facture risk should be acknowledged in patients with chronic pancreatitis, and preventive measures should be considered.

Original languageEnglish
JournalClinical Nutrition
Issue number2
Pages (from-to)395-412
Number of pages18
Publication statusPublished - Feb 2024

Bibliographical note

Copyright © 2023 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.


  • Acute pancreatitis
  • Chronic pancreatitis
  • Medical nutrition
  • Nutrition
  • Nutritional support
  • Pancreatic diseases


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