Establishment of an induced pluripotent stem (iPS) cell line (SDUKIi006-A) from a 21-year old male patient diagnosed with atypical autism disorder

Morad Kamand; Sheena Louise Forsberg; Mads Thomassen; Mirolyuba Ilieva; Morten Meyer; Åsa Fex Svenningsen; Tanja Maria Michel

doi:10.1016/j.scr.2021.102185

Establishment of an induced pluripotent stem (iPS) cell line (SDUKIi006-A) from a 21-year old male patient diagnosed with atypical autism disorder

Morad Kamand^*, Sheena Louise Forsberg, Mads Thomassen, Mirolyuba Ilieva, Morten Meyer, Åsa Fex Svenningsen, Tanja Maria Michel

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

4 Citations (Scopus)

8 Downloads (Pure)

Abstract

Autism is a complex neuropsychiatric disorder defined by significant challenges in communication skills and social behavior as well as repetitive conduct and interests. Recent advances in stem cell technologies allow in vitro modeling of the underlying molecular disease mechanisms. Using integration-free episomal plasmids, we have generated a novel iPS cell line (SDUKIi006-A) from a patient diagnosed with atypical autism (“FYNEN cohort” of Southern Denmark). Characterization of the established cell line validated its expression of pluripotency markers, differentiation into the three germ layers, and the absence of chromosomal abnormalities.

Original language	English
Article number	102185
Journal	Stem Cell Research
Volume	51
ISSN	1873-5061
DOIs	https://doi.org/10.1016/j.scr.2021.102185
Publication status	Published - Mar 2021
Externally published	Yes

Bibliographical note

Funding Information:
We would like to acknowledge Associate Professor Tore Bjerregaard Stage for providing RNA from TMOi001-A cells, and the Psychiatric Research Fund of the Region of Southern Denmark ( Psykiatriens Forskningsfond ; R36-A1784/1808 1 0861 ), Denmark, Faculty of Health Sciences, University of Southern Denmark ( SDUSF‐2016‐144‐(738) ), Denmark, and the JASCHA Foundation , Denmark for financial support ( 6208/1808 2 0861 ).

Publisher Copyright:
© 2021 The Author(s)

Access to Document

10.1016/j.scr.2021.102185Licence: CC BY-NC-ND 4.0

Kamand et al. (2021). Establishment of an induced pluripotent stem (iPS) cell line (SDUKIi006-A) from a 21-year old male patient diagnosed with atypical autism disorderFinal published version, 4.76 MBLicence: CC BY-NC-ND 4.0

AUB Link

Search for the material in Aalborg University Library's search engine

Cite this

@article{faa711c08fb741b6837140f0af72a5fa,

title = "Establishment of an induced pluripotent stem (iPS) cell line (SDUKIi006-A) from a 21-year old male patient diagnosed with atypical autism disorder",

abstract = "Autism is a complex neuropsychiatric disorder defined by significant challenges in communication skills and social behavior as well as repetitive conduct and interests. Recent advances in stem cell technologies allow in vitro modeling of the underlying molecular disease mechanisms. Using integration-free episomal plasmids, we have generated a novel iPS cell line (SDUKIi006-A) from a patient diagnosed with atypical autism (“FYNEN cohort” of Southern Denmark). Characterization of the established cell line validated its expression of pluripotency markers, differentiation into the three germ layers, and the absence of chromosomal abnormalities.",

author = "Morad Kamand and Forsberg, {Sheena Louise} and Mads Thomassen and Mirolyuba Ilieva and Morten Meyer and Svenningsen, {{\AA}sa Fex} and Michel, {Tanja Maria}",

note = "Funding Information: We would like to acknowledge Associate Professor Tore Bjerregaard Stage for providing RNA from TMOi001-A cells, and the Psychiatric Research Fund of the Region of Southern Denmark ( Psykiatriens Forskningsfond ; R36-A1784/1808 1 0861 ), Denmark, Faculty of Health Sciences, University of Southern Denmark ( SDUSF‐2016‐144‐(738) ), Denmark, and the JASCHA Foundation , Denmark for financial support ( 6208/1808 2 0861 ). Publisher Copyright: {\textcopyright} 2021 The Author(s)",

year = "2021",

month = mar,

doi = "10.1016/j.scr.2021.102185",

language = "English",

volume = "51",

journal = "Stem Cell Research",

issn = "1873-5061",

publisher = "Elsevier",

}

TY - JOUR

T1 - Establishment of an induced pluripotent stem (iPS) cell line (SDUKIi006-A) from a 21-year old male patient diagnosed with atypical autism disorder

AU - Kamand, Morad

AU - Forsberg, Sheena Louise

AU - Thomassen, Mads

AU - Ilieva, Mirolyuba

AU - Meyer, Morten

AU - Svenningsen, Åsa Fex

AU - Michel, Tanja Maria

N1 - Funding Information: We would like to acknowledge Associate Professor Tore Bjerregaard Stage for providing RNA from TMOi001-A cells, and the Psychiatric Research Fund of the Region of Southern Denmark ( Psykiatriens Forskningsfond ; R36-A1784/1808 1 0861 ), Denmark, Faculty of Health Sciences, University of Southern Denmark ( SDUSF‐2016‐144‐(738) ), Denmark, and the JASCHA Foundation , Denmark for financial support ( 6208/1808 2 0861 ). Publisher Copyright: © 2021 The Author(s)

PY - 2021/3

Y1 - 2021/3

N2 - Autism is a complex neuropsychiatric disorder defined by significant challenges in communication skills and social behavior as well as repetitive conduct and interests. Recent advances in stem cell technologies allow in vitro modeling of the underlying molecular disease mechanisms. Using integration-free episomal plasmids, we have generated a novel iPS cell line (SDUKIi006-A) from a patient diagnosed with atypical autism (“FYNEN cohort” of Southern Denmark). Characterization of the established cell line validated its expression of pluripotency markers, differentiation into the three germ layers, and the absence of chromosomal abnormalities.

AB - Autism is a complex neuropsychiatric disorder defined by significant challenges in communication skills and social behavior as well as repetitive conduct and interests. Recent advances in stem cell technologies allow in vitro modeling of the underlying molecular disease mechanisms. Using integration-free episomal plasmids, we have generated a novel iPS cell line (SDUKIi006-A) from a patient diagnosed with atypical autism (“FYNEN cohort” of Southern Denmark). Characterization of the established cell line validated its expression of pluripotency markers, differentiation into the three germ layers, and the absence of chromosomal abnormalities.

UR - http://www.scopus.com/inward/record.url?scp=85100198087&partnerID=8YFLogxK

U2 - 10.1016/j.scr.2021.102185

DO - 10.1016/j.scr.2021.102185

M3 - Journal article

C2 - 33524673

AN - SCOPUS:85100198087

SN - 1873-5061

VL - 51

JO - Stem Cell Research

JF - Stem Cell Research

M1 - 102185

ER -

Establishment of an induced pluripotent stem (iPS) cell line (SDUKIi006-A) from a 21-year old male patient diagnosed with atypical autism disorder

Abstract

Bibliographical note

Access to Document

AUB Link

Other files and links

Fingerprint

Cite this