FDG PET/CT in a Patient With Syphilis Suspected of Having Penile Cancer

Jakob Kristian Jakobsen; Joanna Szumniak; Christina Stilling; Joan Fledelius; Kirsten Bouchelouche

doi:10.1097/RLU.0000000000004170

FDG PET/CT in a Patient With Syphilis Suspected of Having Penile Cancer

Jakob Kristian Jakobsen^*, Joanna Szumniak, Christina Stilling, Joan Fledelius, Kirsten Bouchelouche

^*Corresponding author for this work

Research output: Contribution to journal › Comment/debate › Research › peer-review

1 Citation (Scopus)

Abstract

A 58-year-old man with large penile wound and enlarged regional lymph node was suspected of having disseminated penile cancer. FDG PET/CT for primary staging showed high FDG uptake on penis and in several enlarged lymph nodes. However, biopsies revealed no signs of malignancy, but ulceration, inflammation, fibrosis, and spirochetes. Furthermore, Wassermann test was positive. The patient was then treated for syphilis. To our knowledge, this is the first report on FDG PET/CT in a patient suspected of having penile cancer that turned out to be syphilis. Thus, syphilis can be added to the list of benign pitfalls in FDG PET/CT.

Original language	English
Journal	Clinical Nuclear Medicine
Volume	47
Issue number	9
Pages (from-to)	E621-E623
Number of pages	3
ISSN	0363-9762
DOIs	https://doi.org/10.1097/RLU.0000000000004170
Publication status	Published - Sept 2022

Bibliographical note

Keywords

FDG PET/CT
genital
lymph nodes
penile cancer
pitfalls
syphilis
Humans
Middle Aged
Male
Syphilis/complications
Lymphatic Metastasis/pathology
Positron Emission Tomography Computed Tomography
Penile Neoplasms/diagnostic imaging
Lymph Nodes/pathology
Fluorodeoxyglucose F18
Neoplasm Staging
Radiopharmaceuticals

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title = "FDG PET/CT in a Patient With Syphilis Suspected of Having Penile Cancer",

abstract = "A 58-year-old man with large penile wound and enlarged regional lymph node was suspected of having disseminated penile cancer. FDG PET/CT for primary staging showed high FDG uptake on penis and in several enlarged lymph nodes. However, biopsies revealed no signs of malignancy, but ulceration, inflammation, fibrosis, and spirochetes. Furthermore, Wassermann test was positive. The patient was then treated for syphilis. To our knowledge, this is the first report on FDG PET/CT in a patient suspected of having penile cancer that turned out to be syphilis. Thus, syphilis can be added to the list of benign pitfalls in FDG PET/CT.",

keywords = "FDG PET/CT, genital, lymph nodes, penile cancer, pitfalls, syphilis, Humans, Middle Aged, Male, Syphilis/complications, Lymphatic Metastasis/pathology, Positron Emission Tomography Computed Tomography, Penile Neoplasms/diagnostic imaging, Lymph Nodes/pathology, Fluorodeoxyglucose F18, Neoplasm Staging, Radiopharmaceuticals",

author = "Jakobsen, {Jakob Kristian} and Joanna Szumniak and Christina Stilling and Joan Fledelius and Kirsten Bouchelouche",

year = "2022",

month = sep,

doi = "10.1097/RLU.0000000000004170",

language = "English",

volume = "47",

pages = "E621--E623",

journal = "Clinical Nuclear Medicine",

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TY - JOUR

T1 - FDG PET/CT in a Patient With Syphilis Suspected of Having Penile Cancer

AU - Jakobsen, Jakob Kristian

AU - Szumniak, Joanna

AU - Stilling, Christina

AU - Fledelius, Joan

AU - Bouchelouche, Kirsten

PY - 2022/9

Y1 - 2022/9

N2 - A 58-year-old man with large penile wound and enlarged regional lymph node was suspected of having disseminated penile cancer. FDG PET/CT for primary staging showed high FDG uptake on penis and in several enlarged lymph nodes. However, biopsies revealed no signs of malignancy, but ulceration, inflammation, fibrosis, and spirochetes. Furthermore, Wassermann test was positive. The patient was then treated for syphilis. To our knowledge, this is the first report on FDG PET/CT in a patient suspected of having penile cancer that turned out to be syphilis. Thus, syphilis can be added to the list of benign pitfalls in FDG PET/CT.

AB - A 58-year-old man with large penile wound and enlarged regional lymph node was suspected of having disseminated penile cancer. FDG PET/CT for primary staging showed high FDG uptake on penis and in several enlarged lymph nodes. However, biopsies revealed no signs of malignancy, but ulceration, inflammation, fibrosis, and spirochetes. Furthermore, Wassermann test was positive. The patient was then treated for syphilis. To our knowledge, this is the first report on FDG PET/CT in a patient suspected of having penile cancer that turned out to be syphilis. Thus, syphilis can be added to the list of benign pitfalls in FDG PET/CT.

KW - FDG PET/CT

KW - genital

KW - lymph nodes

KW - penile cancer

KW - pitfalls

KW - syphilis

KW - Humans

KW - Middle Aged

KW - Male

KW - Syphilis/complications

KW - Lymphatic Metastasis/pathology

KW - Positron Emission Tomography Computed Tomography

KW - Penile Neoplasms/diagnostic imaging

KW - Lymph Nodes/pathology

KW - Fluorodeoxyglucose F18

KW - Neoplasm Staging

KW - Radiopharmaceuticals

UR - http://www.scopus.com/inward/record.url?scp=85135599981&partnerID=8YFLogxK

U2 - 10.1097/RLU.0000000000004170

DO - 10.1097/RLU.0000000000004170

M3 - Comment/debate

C2 - 35930717

AN - SCOPUS:85135599981

SN - 0363-9762

VL - 47

SP - E621-E623

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

IS - 9

ER -

FDG PET/CT in a Patient With Syphilis Suspected of Having Penile Cancer

Abstract

Bibliographical note

Keywords

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