Abstract
Insufficient blood supply to the heart results in ischemic injury manifested clinically as myocardial infarction (MI). Following ischemia, inflammation is provoked and related to the clinical outcomes. A recent basic science study indicates that complement factor MASP-2 plays an important role in animal models of ischemia/reperfusion injury. We investigated the role of MASP-2 in human acute myocardial ischemia in two clinical settings: (1) Acute MI, and (2) Open heart surgery.
Original language | English |
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Journal | International Journal of Cardiology |
Volume | 166 |
Issue number | 2 |
Pages (from-to) | 499-504 |
Number of pages | 6 |
ISSN | 0167-5273 |
DOIs | |
Publication status | Published - 20 Jun 2013 |