Abstract
The modified Duke criteria requires that Enterococcus faecalis bacteremia must be both community-acquired and without known focus in order to be considered a microbiological "Major" diagnostic criterion in the diagnosis of infective endocarditis. We believe that the microbiological diagnostic criteria should be updated to regard E. faecalis as a "typical" endocarditis bacterium as is currently the case, for example, viridans group streptococci and Staphylococcus aureus. Using data from a prospective study of 344 patients with E. faecalis bacteremia evaluated with echocardiography, we demonstrate that designating E. faecalis as a "typical" endocarditis pathogen, regardless the place of acquisition or the portal of entry, improved the sensitivity to correctly identify definite endocarditis from 70% (modified Duke criteria) to 96% (enterococcal adjusted Duke criteria).
| Original language | English |
|---|---|
| Journal | Clinical Infectious Diseases |
| Volume | 75 |
| Issue number | 6 |
| Pages (from-to) | 1097-1102 |
| Number of pages | 6 |
| ISSN | 1058-4838 |
| DOIs | |
| Publication status | Published - 15 Sept 2022 |
Bibliographical note
© The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.Keywords
- Bacteremia/diagnosis
- Bacteria
- Endocarditis, Bacterial/diagnosis
- Endocarditis/microbiology
- Enterococcus faecalis
- Humans
- Prospective Studies
- community acquired
- enterococcal adjusted duke criteria
- modified duke criteria
- microbiological
- sensitivity