Abstract
Despite its importance, bone health is often neglected in diabetes care.
Type 2 diabetes and osteoporosis often develop simultaneously and represent critical public health challenges globally. Despite a normal or higher bone mineral density, individuals with type 2 diabetes are at increased risk of fractures related to osteoporosis. Consequently, conditional techniques used to detect and diagnose osteoporosis do not adequately identify or predict the risk of fractures associated with low bone quality in people with type 2 diabetes.
This Ph.D. thesis presents the results of three published papers exploring the relationship between type 2 diabetes and bone health in Denmark, covering aspects such as the types of first osteoporotic fractures, diagnostics, and treatment strategies. The findings 1) suggest substantial bone health discrepancies between people with and without type 2 diabetes, 2) indicate a need for optimizing diagnostic and treatment strategies of osteoporosis in individuals with or at risk of type 2 diabetes, and 3) highlight the necessity for further investigation into the relationship between bone and glucose metabolism.
The dearth of focus and acceptance of low bone quality as a diabetes-related complication could well impede fracture prevention in type 2 diabetes. There is an imperative to grasp type 2 diabetes as a risk factor for fractures and change perspectives.
Type 2 diabetes and osteoporosis often develop simultaneously and represent critical public health challenges globally. Despite a normal or higher bone mineral density, individuals with type 2 diabetes are at increased risk of fractures related to osteoporosis. Consequently, conditional techniques used to detect and diagnose osteoporosis do not adequately identify or predict the risk of fractures associated with low bone quality in people with type 2 diabetes.
This Ph.D. thesis presents the results of three published papers exploring the relationship between type 2 diabetes and bone health in Denmark, covering aspects such as the types of first osteoporotic fractures, diagnostics, and treatment strategies. The findings 1) suggest substantial bone health discrepancies between people with and without type 2 diabetes, 2) indicate a need for optimizing diagnostic and treatment strategies of osteoporosis in individuals with or at risk of type 2 diabetes, and 3) highlight the necessity for further investigation into the relationship between bone and glucose metabolism.
The dearth of focus and acceptance of low bone quality as a diabetes-related complication could well impede fracture prevention in type 2 diabetes. There is an imperative to grasp type 2 diabetes as a risk factor for fractures and change perspectives.
| Original language | English |
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| Electronic ISBNs | 978-87-7573-704-8 |
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| Publication status | Published - 2023 |