Candidate genetic pathways for attention-deficit/hyperactivity disorder (ADHD) show association to hyperactive/impulsive symptoms in children with ADHD

Janita Bralten, Barbara Franke, Irwin Waldman, Nanda Rommelse, Catharina Hartman, Philip Asherson, Tobias Banaschewski, Richard P Ebstein, Michael Gill, Ana Miranda, Robert D Oades, Herbert Roeyers, Aribert Rothenberger, Joseph A Sergeant, Jaap Oosterlaan, Edmund Sonuga-Barke, Hans-Christoph Steinhausen, Stephen V Faraone, Jan K Buitelaar, Alejandro Arias-Vásquez

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69 Citationer (Scopus)

Abstract

Because multiple genes with small effect sizes are assumed to play a role in attention-deficit/hyperactivity disorder (ADHD) etiology, considering multiple variants within the same analysis likely increases the total explained phenotypic variance, thereby boosting the power of genetic studies. This study investigated whether pathway-based analysis could bring scientists closer to unraveling the biology of ADHD.
OriginalsprogEngelsk
TidsskriftJournal of the American Academy of Child and Adolescent Psychiatry
Vol/bind52
Udgave nummer11
Sider (fra-til)1204-1212.e1
ISSN0890-8567
DOI
StatusUdgivet - nov. 2013

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