TY - JOUR
T1 - Prevalence of red panda amdoparvovirus infection in European zoos
AU - Kuhar, Urška
AU - Tomášek, Oldřich
AU - Sós, Endre
AU - Mede, Jana
AU - Kastelic, Marjan
AU - Jež, Nuša
AU - Petrikova, Michaela
AU - Jensen, Trine Hammer
AU - Alex, Charles Everett
AU - Jamnikar-Ciglenecki, Urška
AU - Kvapil, Pavel
N1 - Copyright © 2023 Kuhar, Tomášek, Sós, Mede, Kastelic, Jež, Petrikova, Jensen, Alex, Jamnikar-Ciglenecki and Kvapil.
PY - 2023
Y1 - 2023
N2 - Red panda amdoparvovirus (RPAV) was first described in captive red pandas (Ailurus fulgens) at a zoo in the United States in 2018. Subsequently, the prevalence of infection in zoos in the United States was reported to be 50%; however, RPAV prevalence outside the United States remains unstudied. This study was conducted to investigate the prevalence of RPAV in 134 red pandas from zoos in Europe. Overall, RPAV was detected with PCR in 21 of 62 zoos (33.9%), and the virus prevalence among individuals was estimated to be 24.2% (95% confidence interval, 17.4%–32.0%). Remarkably, adult females tested positive for RPAV more frequently than adult males. Zoos where RPAV was detected reported a significantly higher occurrence of alopecia (and clinical signs in general), whereas other commonly reported problems (fecal disorders and dental disease) showed no difference. A repeated pooled sampling of two positive individuals further showed that RPAV excretion in feces is intermittent, with the viral DNA being only detected on 8 out of 14 sampling days. The intermittent nature of excretion implies that RPAV prevalence may be higher than the estimated value.
AB - Red panda amdoparvovirus (RPAV) was first described in captive red pandas (Ailurus fulgens) at a zoo in the United States in 2018. Subsequently, the prevalence of infection in zoos in the United States was reported to be 50%; however, RPAV prevalence outside the United States remains unstudied. This study was conducted to investigate the prevalence of RPAV in 134 red pandas from zoos in Europe. Overall, RPAV was detected with PCR in 21 of 62 zoos (33.9%), and the virus prevalence among individuals was estimated to be 24.2% (95% confidence interval, 17.4%–32.0%). Remarkably, adult females tested positive for RPAV more frequently than adult males. Zoos where RPAV was detected reported a significantly higher occurrence of alopecia (and clinical signs in general), whereas other commonly reported problems (fecal disorders and dental disease) showed no difference. A repeated pooled sampling of two positive individuals further showed that RPAV excretion in feces is intermittent, with the viral DNA being only detected on 8 out of 14 sampling days. The intermittent nature of excretion implies that RPAV prevalence may be higher than the estimated value.
KW - Ailurus fulgens
KW - amdoparvovirus
KW - red panda
KW - RPAV
KW - zoo
UR - http://www.scopus.com/inward/record.url?scp=85176240879&partnerID=8YFLogxK
U2 - 10.3389/fvets.2023.1276248
DO - 10.3389/fvets.2023.1276248
M3 - Journal article
C2 - 37954668
AN - SCOPUS:85176240879
SN - 2297-1769
VL - 10
JO - Frontiers in Veterinary Science
JF - Frontiers in Veterinary Science
M1 - 1276248
ER -