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Abstract
Aim: To perform an early cost-effectiveness analysis of in vitro expanded myoblasts (IVM) and minced myofibers versus midurethral slings (MUS) for surgical treatment of female stress urinary incontinence. Methods: Cost-effectiveness and sensitivity analyses were performed using a decision tree comprising previously published data and expert opinions. Results & conclusion: In the base case scenario, MUS was the cost-effective strategy with a negative incremental cost-effectiveness ratio compared with IVM and a positive incremental cost-effectiveness ratio compared with minced myofibers. However, the sensitivity analysis indicates that IVM may become an alternative providing greater effect at a higher cost. With the possibility of becoming more effective, IVM treatment would be advantageous over MUS given its reduced invasiveness and lower risks of complications.
Translated title of the contribution | Cellebaseret terapi til behandling af kvindelig stressininkontinens: en tidlig omkostningseffektivitetsanalyse |
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Original language | English |
Journal | Regenerative Medicine |
Volume | 13 |
Issue number | 3 |
Pages (from-to) | 321-330 |
Number of pages | 10 |
ISSN | 1746-0751 |
DOIs | |
Publication status | Published - 1 May 2018 |
Keywords
- cell- and tissue-based therapy
- economic analysis
- healthcare costs
- incremental cost-effectiveness ratio
- midurethral slings
- myoblast transplantation
- stress urinary incontinence
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Dive into the research topics of 'Cell-based therapy for the treatment of female stress urinary incontinence: an early cost–effectiveness analysis'. Together they form a unique fingerprint.Activities
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Managament Board of the COST Action BM1209 (External organisation)
Pablo Pennisi (Member)
2013 → 2017Activity: Memberships › Membership of research networks or expert groups