TY - JOUR
T1 - Clinical use of lithium salts
T2 - guide for users and prescribers
AU - Tondo, L.
AU - Alda, M.
AU - Bauer, M.
AU - Bergink, V.
AU - Grof, P.
AU - Hajek, T.
AU - Lewitka, U.
AU - Licht, R.W.
AU - Manchia, M.
AU - Müller-Oerlinghausen, B.
AU - Nielsen, R.E.
AU - Selo, M.
AU - Simhandl, C.
AU - Baldessarini, R.J.
AU - International Group for Studies of Lithium (IGSLi)
PY - 2019/7/22
Y1 - 2019/7/22
N2 - Background: Lithium has been used clinically for 70 years, mainly to treat bipolar disorder. Competing treatments and exaggerated impressions about complexity and risks of lithium treatment have led to its declining use in some countries, encouraging this update about its safe clinical use. We conducted a nonsystematic review of recent research reports and developed consensus among international experts on the use of lithium to treat major mood disorders, aiming for a simple but authoritative guide for patients and prescribers. Main text: We summarized recommendations concerning safe clinical use of lithium salts to treat major mood disorders, including indications, dosing, clinical monitoring, adverse effects and use in specific circumstances including during pregnancy and for the elderly. Conclusions: Lithium continues as the standard and most extensively evaluated treatment for bipolar disorder, especially for long-term prophylaxis.
AB - Background: Lithium has been used clinically for 70 years, mainly to treat bipolar disorder. Competing treatments and exaggerated impressions about complexity and risks of lithium treatment have led to its declining use in some countries, encouraging this update about its safe clinical use. We conducted a nonsystematic review of recent research reports and developed consensus among international experts on the use of lithium to treat major mood disorders, aiming for a simple but authoritative guide for patients and prescribers. Main text: We summarized recommendations concerning safe clinical use of lithium salts to treat major mood disorders, including indications, dosing, clinical monitoring, adverse effects and use in specific circumstances including during pregnancy and for the elderly. Conclusions: Lithium continues as the standard and most extensively evaluated treatment for bipolar disorder, especially for long-term prophylaxis.
KW - Bipolar disorder
KW - Blood testing
KW - Dosing
KW - Lithium
KW - Side-effects
UR - http://www.scopus.com/inward/record.url?scp=85069477845&partnerID=8YFLogxK
U2 - 10.1186/s40345-019-0151-2
DO - 10.1186/s40345-019-0151-2
M3 - Review article
C2 - 31328245
SN - 2194-7511
VL - 7
SP - 1
EP - 10
JO - International Journal of Bipolar Disorders
JF - International Journal of Bipolar Disorders
IS - 1
M1 - 16
ER -