Abstract
OBJECTIVE: The objective of this study was to estimate the area fraction of different ratios of Bio-Oss(®) and bone, prior to grafting in an in vitro model to demonstrate a histomorphometric baseline.
METHODS: Bio-Oss(®) particles were mixed with autogenous bone from pig jaw in three different ratios (50:50, 80:20 and 100:0) and packed in rice paper in a standardized procedure. Histomorphometric analyses were performed in 25 specimens and 74 regions of interest. The area percentage of Bio-Oss(®) , bone, and non-mineralized tissue (NMT) were calculated. Results were reported as mean values and 95% confidence interval (CI).
RESULTS: The mean area fraction of Bio-Oss(®) was 20.6% (CI: 18.2-23) in the 50:50 mixture, 33.6% (CI: 29.7-37.6) in the 80:20 mixture, and 43.4% (CI: 40.5-46.3) in the 100:0 mixture. The mean area fraction of NMT was 60.5% (CI: 57.9-63.1) in the 50:50 mixture, 59.6% (CI: 56.4-62.7) in the 80:20 mixture, and 56.6% (CI: 53.7-59.5) in the 100:0 mixture. The mean area fraction of bone was 18.9% (CI: 16.9-20.9) in the 50:50 mixture and 6.8% (CI: 5-8.6) in the 80:20 mixture.
CONCLUSION: There is a great difference in the clinically estimated percentage and the histomorphometrically evaluated percentage of Bio-Oss(®) at baseline, prior to grafting. The area fraction of different tissues presented in this study may be beneficial as guidance for histomorphometrical baseline calculations when different mixtures of Bio-Oss(®) and autogenous bone are used as grafting materials.
Original language | English |
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Journal | Clinical Oral Implants Research |
Volume | 29 |
Issue number | 2 |
Pages (from-to) | 185-191 |
Number of pages | 7 |
ISSN | 0905-7161 |
DOIs | |
Publication status | Published - Feb 2018 |
Keywords
- alveolar ridge augmentation
- bone substitute
- dental implants
- histology
- sinus floor augmentation
- Animals
- Swine
- Jaw/pathology
- Bone Transplantation/methods
- Orthognathic Surgical Procedures
- In Vitro Techniques
- Minerals/administration & dosage