Prognostic impact of clinician-based interpretation of 18F-fluorodeoxyglucose positron emission tomography/computed tomography reports obtained in patients with newly diagnosed diffuse large B-cell lymphoma

Karen J Mylam; Tarec C El-Galaly; Martin Hutchings; Peter Brown; Bodil Himmelstrup; Oke Gerke; Dorte Gillstrøm; Ida Blok Sillesen; Lars Munksgaard; Bjarne B Pedersen; Ilse Christiansen; Paw Jensen; Anne L Nielsen; Lars M Pedersen

doi:10.3109/10428194.2013.850165

Prognostic impact of clinician-based interpretation of ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography reports obtained in patients with newly diagnosed diffuse large B-cell lymphoma

Karen J Mylam, Tarec C El-Galaly, Martin Hutchings, Peter Brown, Bodil Himmelstrup, Oke Gerke, Dorte Gillstrøm, Ida Blok Sillesen, Lars Munksgaard, Bjarne B Pedersen, Ilse Christiansen, Paw Jensen, Anne L Nielsen, Lars M Pedersen

Research output: Contribution to journal › Journal article › Research › peer-review

8 Citations (Scopus)

Abstract

The aim of this study was to evaluate the prognostic value of clinician interpretation of positron emission tomography/computed tomography (PET/CT) reports at mid-therapy, interim PET (I-PET) and after the end of first-line therapy (E-PET) in patients with diffuse large B-cell lymphoma (DLBCL). Four hundred and thirty patients were enrolled in this study comprising a total of 617 PET reports. Each report was evaluated by three expert hematologists randomly selected from a panel of nine. Reports were labeled positive or negative if all three interpreters agreed. All others were considered indeterminate. Indeterminate reports accounted for 59% of I-PET and 49% of E-PET reports. Two-year overall survival (OS) for patients with a positive, indeterminate and negative I-PET was 58%, 87% and 89% (p

Original language	English
Journal	Leukemia and Lymphoma
Volume	55
Issue number	7
Pages (from-to)	1563-1569
Number of pages	7
ISSN	1042-8194
DOIs	https://doi.org/10.3109/10428194.2013.850165
Publication status	Published - 2014

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Mylam, K. J., El-Galaly, T. C., Hutchings, M., Brown, P., Himmelstrup, B., Gerke, O., Gillstrøm, D., Sillesen, I. B., Munksgaard, L., Pedersen, B. B., Christiansen, I., Jensen, P., Nielsen, A. L., & Pedersen, L. M. (2014). Prognostic impact of clinician-based interpretation of ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography reports obtained in patients with newly diagnosed diffuse large B-cell lymphoma. Leukemia and Lymphoma, 55(7), 1563-1569. https://doi.org/10.3109/10428194.2013.850165

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title = "Prognostic impact of clinician-based interpretation of 18F-fluorodeoxyglucose positron emission tomography/computed tomography reports obtained in patients with newly diagnosed diffuse large B-cell lymphoma",

abstract = "The aim of this study was to evaluate the prognostic value of clinician interpretation of positron emission tomography/computed tomography (PET/CT) reports at mid-therapy, interim PET (I-PET) and after the end of first-line therapy (E-PET) in patients with diffuse large B-cell lymphoma (DLBCL). Four hundred and thirty patients were enrolled in this study comprising a total of 617 PET reports. Each report was evaluated by three expert hematologists randomly selected from a panel of nine. Reports were labeled positive or negative if all three interpreters agreed. All others were considered indeterminate. Indeterminate reports accounted for 59% of I-PET and 49% of E-PET reports. Two-year overall survival (OS) for patients with a positive, indeterminate and negative I-PET was 58%, 87% and 89% (p ",

author = "Mylam, {Karen J} and El-Galaly, {Tarec C} and Martin Hutchings and Peter Brown and Bodil Himmelstrup and Oke Gerke and Dorte Gillstr{\o}m and Sillesen, {Ida Blok} and Lars Munksgaard and Pedersen, {Bjarne B} and Ilse Christiansen and Paw Jensen and Nielsen, {Anne L} and Pedersen, {Lars M}",

year = "2014",

doi = "10.3109/10428194.2013.850165",

language = "English",

volume = "55",

pages = "1563--1569",

journal = "Leukemia and Lymphoma",

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Mylam, KJ, El-Galaly, TC, Hutchings, M, Brown, P, Himmelstrup, B, Gerke, O, Gillstrøm, D, Sillesen, IB, Munksgaard, L, Pedersen, BB, Christiansen, I, Jensen, P, Nielsen, AL & Pedersen, LM 2014, 'Prognostic impact of clinician-based interpretation of ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography reports obtained in patients with newly diagnosed diffuse large B-cell lymphoma', Leukemia and Lymphoma, vol. 55, no. 7, pp. 1563-1569. https://doi.org/10.3109/10428194.2013.850165

Prognostic impact of clinician-based interpretation of ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography reports obtained in patients with newly diagnosed diffuse large B-cell lymphoma. / Mylam, Karen J; El-Galaly, Tarec C; Hutchings, Martin et al.
In: Leukemia and Lymphoma, Vol. 55, No. 7, 2014, p. 1563-1569.

Research output: Contribution to journal › Journal article › Research › peer-review

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T1 - Prognostic impact of clinician-based interpretation of 18F-fluorodeoxyglucose positron emission tomography/computed tomography reports obtained in patients with newly diagnosed diffuse large B-cell lymphoma

AU - Mylam, Karen J

AU - El-Galaly, Tarec C

AU - Hutchings, Martin

AU - Brown, Peter

AU - Himmelstrup, Bodil

AU - Gerke, Oke

AU - Gillstrøm, Dorte

AU - Sillesen, Ida Blok

AU - Munksgaard, Lars

AU - Pedersen, Bjarne B

AU - Christiansen, Ilse

AU - Jensen, Paw

AU - Nielsen, Anne L

AU - Pedersen, Lars M

PY - 2014

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AB - The aim of this study was to evaluate the prognostic value of clinician interpretation of positron emission tomography/computed tomography (PET/CT) reports at mid-therapy, interim PET (I-PET) and after the end of first-line therapy (E-PET) in patients with diffuse large B-cell lymphoma (DLBCL). Four hundred and thirty patients were enrolled in this study comprising a total of 617 PET reports. Each report was evaluated by three expert hematologists randomly selected from a panel of nine. Reports were labeled positive or negative if all three interpreters agreed. All others were considered indeterminate. Indeterminate reports accounted for 59% of I-PET and 49% of E-PET reports. Two-year overall survival (OS) for patients with a positive, indeterminate and negative I-PET was 58%, 87% and 89% (p

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DO - 10.3109/10428194.2013.850165

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