TY - JOUR
T1 - Combined intra-articular glucocorticoid, bupivacaine and morphine reduces pain and convalescence after diagnostic knee arthroscopy
AU - Rasmussen, Sten
AU - Lorentzen, Jan S.
AU - Larsen, Allan S.
AU - Thomsen, Søren T.
AU - Kehlet, Henrik
PY - 2002
Y1 - 2002
N2 - We studied the effect of intra-articular saline vs. bupivacaine + morphine or bupivacaine + morphine + methylprednisolone after diagnostic knee arthroscopy. In a double-blind randomized study, 60 patients undergoing diagnostic knee arthroscopy without a therapeutic procedure were allocated to groups receiving intra-articular saline, intra-articular bupivacaine 150 mg + morphine 4 mg or the same dose of bupivacaine + morphine + intra-articular methylprednisolone 40 mg at the end of arthroscopy during general anesthesia. All patients were instructed to resume normal activities immediately after the procedure. Pain during movement and walking, leg muscle force and joint effusion, use of crutches and duration of sick leave were assessed. A combination of bupivacaine and morphine reduced pain, duration of immobilization and of convalescence. The addition of methylprednisolone further reduced pain, use of more analgesics, joint swelling and convalescence.
AB - We studied the effect of intra-articular saline vs. bupivacaine + morphine or bupivacaine + morphine + methylprednisolone after diagnostic knee arthroscopy. In a double-blind randomized study, 60 patients undergoing diagnostic knee arthroscopy without a therapeutic procedure were allocated to groups receiving intra-articular saline, intra-articular bupivacaine 150 mg + morphine 4 mg or the same dose of bupivacaine + morphine + intra-articular methylprednisolone 40 mg at the end of arthroscopy during general anesthesia. All patients were instructed to resume normal activities immediately after the procedure. Pain during movement and walking, leg muscle force and joint effusion, use of crutches and duration of sick leave were assessed. A combination of bupivacaine and morphine reduced pain, duration of immobilization and of convalescence. The addition of methylprednisolone further reduced pain, use of more analgesics, joint swelling and convalescence.
UR - http://www.scopus.com/inward/record.url?scp=0036259154&partnerID=8YFLogxK
U2 - 10.1080/000164702753671768
DO - 10.1080/000164702753671768
M3 - Journal article
C2 - 12079015
AN - SCOPUS:0036259154
SN - 0001-6470
VL - 73
SP - 175
EP - 178
JO - Acta Orthopaedica Scandinavica
JF - Acta Orthopaedica Scandinavica
IS - 2
ER -