Long-term follow-up after modern radical prostate cancer radiotherapy: exploring the use of a NI TI stent and MRI delineation

Bidragets oversatte titel: Langtidsbivirkninger efter intenderet kurativ strålebeahdnling for prostata cancer: med brug af en NI TI stent og MRI indtegning

Publikation: Bog/antologi/afhandling/rapportPh.d.-afhandlingForskning

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Abstrakt

A significant increase in the prostate cancer incidence has made prostate cancer a major health problem in recent years. Because of the often but unfortunately not always indolent nature of the disease, over-diagnosis and over-treatment are relevant clinical and ethic dilemmas.
External beam radiotherapy is a well established treatment modality for prostate cancer. Accuracy and precision are key words with regard to optimal survival and minimal toxicity in modern radiotherapy and are fundamentals in modern radiotherapy.
Modern imaging has improved the ability to define radiotherapy target volumes. Especially treatment margins have been reduced through the use of more accurate treatment planning and image-guided technology.
Increasing doses have lead to increased disease control. Aiming for minimal toxicity after radiotherapy, magnetic resonance imaging delineation could be a possible tool, knowing that clinical target volumes are up to 30% smaller on MRI delineation compared to computer tomography delineation.
The overall aim of the thesis was to explore the use of MRI target planning and a Nicle-Titanium prostate stent as fiducial marker for both MR-CT co-registration and image guided radiotherapy.
Bidragets oversatte titelLangtidsbivirkninger efter intenderet kurativ strålebeahdnling for prostata cancer: med brug af en NI TI stent og MRI indtegning
OriginalsprogEngelsk
ForlagAalborg Universitetsforlag
Antal sider125
ISBN (Elektronisk)978-87-7112-289-3
DOI
StatusUdgivet - 2016
NavnPh.d.-serien for Det Sundhedsvidenskabelige Fakultet, Aalborg Universitet
ISSN2246-1302

Bibliografisk note

Jesper Carl, Hovedvejleder
Niels-Christian Langkilde, Bivejleder

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