Abstract
The quantitative data observed from analysing STR DNA is a mixture of contributions from various sources. Apart from the true allelic peaks, the observed signal consists of at least three components resulting from the measurement technique and the PCR amplification:
- Background noise (random noise due to the apparatus used for measurements).
- Pull-up effects (more systematic increase caused by overlap in the spectrum)
- Stutters (peaks located four basepairs before the true peak).
We present filtering techniques for all three technical artifacts based on statistical analysis of data from controlled experiments conducted at The Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health Sciences, Universityof Copenhagen, Denmark.
| Original language | English |
|---|---|
| Publication date | 2009 |
| Number of pages | 1 |
| Publication status | Published - 2009 |
| Event | ICFIS 2008 (International Conference on Forensic Inference and Statistics) - Lausanne, Switzerland Duration: 20 Aug 2008 → 23 Aug 2008 Conference number: 7 |
Conference
| Conference | ICFIS 2008 (International Conference on Forensic Inference and Statistics) |
|---|---|
| Number | 7 |
| Country/Territory | Switzerland |
| City | Lausanne |
| Period | 20/08/2008 → 23/08/2008 |