Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial

Boris Modrau; Grethe Andersen; Irene Klærke Mikkelsen; Anne Nielsen; Mikkel Bo Hansen; Martin Berg Johansen; Helle Wulf Eskildsen; Jan Plougmann Povlsen; Yousef Yavarian; Kim Mouridsen; Leif Østergaard; Flemming Winther Bach; Niels Hjort

doi:10.1161/STROKEAHA.119.027446

Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial

Boris Modrau^*, Grethe Andersen, Irene Klærke Mikkelsen, Anne Nielsen, Mikkel Bo Hansen, Martin Berg Johansen, Helle Wulf Eskildsen, Jan Plougmann Povlsen, Yousef Yavarian, Kim Mouridsen, Leif Østergaard, Flemming Winther Bach, Niels Hjort

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

1 Citation (Scopus)

Original language	English
Journal	Stroke
Volume	51
Issue number	7
Pages (from-to)	1983-1990
Number of pages	8
ISSN	0039-2499
DOIs	https://doi.org/10.1161/STROKEAHA.119.027446
Publication status	Published - Jul 2020

Keywords

clinical trial
neuroprotective drugs
reperfusion
stroke
theophylline
thrombolytic therapy
tissue-type plasminogen activator

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10.1161/STROKEAHA.119.027446

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Modrau, B., Andersen, G., Mikkelsen, I. K., Nielsen, A., Hansen, M. B., Johansen, M. B., Eskildsen, H. W., Povlsen, J. P., Yavarian, Y., Mouridsen, K., Østergaard, L., Bach, F. W., & Hjort, N. (2020). Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial. Stroke, 51(7), 1983-1990. https://doi.org/10.1161/STROKEAHA.119.027446

Modrau, Boris ; Andersen, Grethe ; Mikkelsen, Irene Klærke ; Nielsen, Anne ; Hansen, Mikkel Bo ; Johansen, Martin Berg ; Eskildsen, Helle Wulf ; Povlsen, Jan Plougmann ; Yavarian, Yousef ; Mouridsen, Kim ; Østergaard, Leif ; Bach, Flemming Winther ; Hjort, Niels. / Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke : A Randomized Placebo-Controlled Trial. In: Stroke. 2020 ; Vol. 51, No. 7. pp. 1983-1990.

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title = "Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial",

keywords = "clinical trial, neuroprotective drugs, reperfusion, stroke, theophylline, thrombolytic therapy, tissue-type plasminogen activator",

author = "Boris Modrau and Grethe Andersen and Mikkelsen, {Irene Kl{\ae}rke} and Anne Nielsen and Hansen, {Mikkel Bo} and Johansen, {Martin Berg} and Eskildsen, {Helle Wulf} and Povlsen, {Jan Plougmann} and Yousef Yavarian and Kim Mouridsen and Leif {\O}stergaard and Bach, {Flemming Winther} and Niels Hjort",

year = "2020",

month = jul,

doi = "10.1161/STROKEAHA.119.027446",

language = "English",

volume = "51",

pages = "1983--1990",

journal = "Stroke",

issn = "0039-2499",

publisher = "Lippincott Williams & Wilkins",

number = "7",

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Modrau, B, Andersen, G, Mikkelsen, IK, Nielsen, A, Hansen, MB, Johansen, MB , Eskildsen, HW , Povlsen, JP , Yavarian, Y, Mouridsen, K, Østergaard, L, Bach, FW & Hjort, N 2020, 'Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial', Stroke, vol. 51, no. 7, pp. 1983-1990. https://doi.org/10.1161/STROKEAHA.119.027446

Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke : A Randomized Placebo-Controlled Trial. / Modrau, Boris; Andersen, Grethe; Mikkelsen, Irene Klærke; Nielsen, Anne; Hansen, Mikkel Bo; Johansen, Martin Berg ; Eskildsen, Helle Wulf ; Povlsen, Jan Plougmann ; Yavarian, Yousef; Mouridsen, Kim; Østergaard, Leif; Bach, Flemming Winther; Hjort, Niels.

In: Stroke, Vol. 51, No. 7, 07.2020, p. 1983-1990.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke

T2 - A Randomized Placebo-Controlled Trial

AU - Modrau, Boris

AU - Andersen, Grethe

AU - Mikkelsen, Irene Klærke

AU - Nielsen, Anne

AU - Hansen, Mikkel Bo

AU - Johansen, Martin Berg

AU - Eskildsen, Helle Wulf

AU - Povlsen, Jan Plougmann

AU - Yavarian, Yousef

AU - Mouridsen, Kim

AU - Østergaard, Leif

AU - Bach, Flemming Winther

AU - Hjort, Niels

PY - 2020/7

Y1 - 2020/7

KW - clinical trial

KW - neuroprotective drugs

KW - reperfusion

KW - stroke

KW - theophylline

KW - thrombolytic therapy

KW - tissue-type plasminogen activator

UR - http://www.scopus.com/inward/record.url?scp=85086938156&partnerID=8YFLogxK

U2 - 10.1161/STROKEAHA.119.027446

DO - 10.1161/STROKEAHA.119.027446

M3 - Journal article

C2 - 32568651

AN - SCOPUS:85086938156

VL - 51

SP - 1983

EP - 1990

JO - Stroke

JF - Stroke

SN - 0039-2499

IS - 7

ER -

Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial

Keywords

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Neuroprotective effect of theophylline in acute ischemic stroke

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