Publikationer pr. år
Publikationer pr. år
Abstract
This PhD thesis aimed to explore the role of the immune system in recurrent pregnancy loss (RPL) pathogenesis and the effect of immunomodulatory treatments. The thesis contains four original research articles investigating the association between specific immune biomarkers and RPL and one randomized controlled trial protocol for an ongoing placebo-controlled trial that aims to examine the clinical and immunomodulatory effects of intravenous immunoglobulin combined with low-dose oral glucocorticoid treatment as well as the presence of immune biomarkers among women with RPL undergoing artificial reproductive technology treatment.
The introduction includes a description of the epidemiology and etiology of RPL. Furthermore, a brief description of the current knowledge of the immunological role in normal pregnancy and the immune system aberrations found in patients with RPL is given. Finally, treatments recommended for patients with RPL and immunomodulatory treatments under investigation are presented.
The introduction includes a description of the epidemiology and etiology of RPL. Furthermore, a brief description of the current knowledge of the immunological role in normal pregnancy and the immune system aberrations found in patients with RPL is given. Finally, treatments recommended for patients with RPL and immunomodulatory treatments under investigation are presented.
| Bidragets oversatte titel | Gentagne graviditetstab: immunologiske risikofaktorer og immunmodulerende behandlinger |
|---|---|
| Originalsprog | Engelsk |
| Vejledere |
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| Udgiver | |
| ISBN'er, elektronisk | 978-87-7573-665-2 |
| DOI | |
| Status | Udgivet - 2023 |
Publikation
- 4 Tidsskriftartikel
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A combination of the HLA-DRB1*03 phenotype and low plasma mannose-binding lectin predisposes to autoantibody formation in women with recurrent pregnancy loss
Nørgaard-Pedersen, C., Steffensen, R., Kesmodel, U. S. & Christiansen, O. B., 26 jan. 2023, I: Frontiers in Immunology. 14, 1069974.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil2 Citationer (Scopus)43 Downloads (Pure) -
Maternal carriage of H-Y restricting HLA class II alleles is a negative prognostic factor for women with recurrent pregnancy loss after birth of a boy
Nørgaard-Pedersen, C., Steffensen, R., Kesmodel, U. S. & Christiansen, O. B., mar. 2023, I: Journal of Reproductive Immunology. 156, 8 s., 103817.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil59 Downloads (Pure) -
Plasma level of mannose-binding lectin is associated with the risk of recurrent pregnancy loss but not pregnancy outcome after the diagnosis
Nørgaard-Pedersen, C., Rom, L. H., Steffensen, R., Kesmodel, U. S. & Christiansen, O. B., 2022, I: Human reproduction open. 2022, 3, hoac024.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil3 Citationer (Scopus)43 Downloads (Pure)